CT Image Fusion via Deformation Model for Multi-State Visualization
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Solution Overview
Problem
Computed tomography systems face challenges in simultaneously acquiring projection data for different physiological states, such as respiration and contrast enhancement, due to differing dynamic behaviors and limited field of view, which restricts the ability to visualize multiple states in a single medical image.
Innovation Solution
A method involving the acquisition of first and second projection data from overlapping measurement regions, registration of a reference image to produce a deformation model, and combination of deformed functional images with respiration-correlated images to generate a comprehensive medical image, utilizing a computed tomography system with an X-ray source and detector, and a processing unit for image reconstruction and processing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If the imaging measurement sequence is optimized for acquiring respiration-correlated images, then the quality of respiration images is improved, but the ability to simultaneously acquire functional images with different dynamic behavior deteriorates
Solution Approach 1:
The patent divides the measurement process into two separate imaging measurement sequences: a first sequence optimized for respiration-correlated images and a second sequence optimized for functional images. Each sequence can be independently optimized for its specific physiological state without compromising the other, thereby resolving the contradiction between image quality and multi-state visualization capability
Solution Approach 2:
The patent creates a unified medical image that combines both respiration-correlated information and functional information (such as contrast enhancement or iodine distribution) into a single comprehensive image. This multi-functional image serves multiple diagnostic purposes simultaneously, enabling visualization of different physiological states while maintaining optimization for each specific state during acquisition
2Device complexity
If the field of view is limited to the maximum capability of the imaging modality, then the device complexity is reduced, but the measurement region needed for simultaneous acquisition of multiple physiological states cannot be covered
Solution Approach 1:
The patent divides the large measurement region into two overlapping measurement regions: a first measurement region for respiration-correlated images and a second measurement region for functional images. Each region can be covered by the standard maximum field of view of the CT apparatus, avoiding the need for complex extended-field-of-view hardware while still enabling comprehensive coverage of the entire anatomical area of interest
Solution Approach 2:
The patent uses one measurement region nested within or overlapping with another measurement region. The first and second measurement regions overlap at least partially, allowing both regions to be covered by the standard field of view capability of the CT apparatus while collectively covering a larger effective measurement area than either region alone
3Device complexity
If projection data for different physiological states are acquired in succession, then the device complexity is reduced, but the examination time and X-ray dose increase
Solution Approach 1:
The patent performs both first and second imaging measurement sequences in a continuous manner without significant interruption between them. The sequences are executed back-to-back, minimizing idle time and maintaining continuous X-ray acquisition and table movement, thereby reducing total examination time while keeping the acquisition system relatively simple
Solution Approach 2:
The patent structures the acquisition as two distinct periodic measurement sequences, where each sequence is optimized for its specific physiological state and executed in a systematic, repeating pattern. This periodic structure allows for efficient resource utilization and streamlined processing, reducing overall examination time compared to more ad-hoc acquisition approaches
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables the creation of medical images that incorporate multiple physiological states, improving radiation treatment planning and reducing the length and X-ray dose of examinations by combining respiration-correlated and functional image information.
Implementation Method 1
the computed tomography apparatus comprises at least one X-ray source and at least one X-ray detector
Data Source
AI summary
A method is for providing a medical image of a patient, acquired via a computed tomography apparatus. An embodiment of the method includes acquiring first projection data of a first measurement region; acquiring second projection data of a second measurement region; registering a reference image to the at least one respiration-correlated image of the patient, wherein the reference image corresponds to the at least one functional image of the patient or is reconstructed under a second reconstruction rule from the second projection data, to produce a deformation model; applying the deformation model to the at least one functional image of the patient; combining the at least one functional image of the patient, deformed by the applying of the deformation model, with the at least one respiration-correlated image of the patient, to produce the medical image of the patient; and providing the medical image of the patient.