Simultaneous CT-MRI Reconstruction via Structural Coupling

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Solution Overview

Problem

Current imaging modalities, such as CT and MRI, have limitations in depicting complex dynamics of mammalian physiology and pathology, with inefficient and inaccurate reconstruction techniques, and challenges in combining data due to space constraints and electromagnetic interference.

Innovation Solution

The integration of structural coupling (SC) and compressive sensing (CS) techniques for simultaneous CT-MRI image reconstruction, allowing bidirectional image estimation and improved image quality by connecting data from both modalities, with CT and MRI serving as prior knowledge to each other.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If separate CT and MRI scans are performed individually, then each modality can be optimized independently, but the scanning time increases and the anatomic localization accuracy deteriorates due to post-acquisition image fusion errors

Engineering Contradiction:
Improveanatomic localization accuracyVSAvoidscanning time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent combines CT and MRI scanning capabilities into a single integrated hybrid scanner system, allowing both modalities to acquire data simultaneously from the same patient position. This merging eliminates the need for separate scans and subsequent image fusion, thereby improving anatomic localization accuracy while reducing total scanning time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system performs preliminary spatial registration and coordination of CT and MRI acquisition parameters before actual scanning begins. This preliminary setup ensures that both modalities are pre-aligned to capture data from identical anatomical positions, preventing fusion errors and eliminating the need for post-acquisition registration adjustments.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If advanced reconstruction techniques are used to improve image quality, then diagnostic performance improves, but computational complexity and processing time increase

Engineering Contradiction:
Improveimage qualityVSAvoidreconstruction complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements an iterative reconstruction algorithm that uses feedback loops to progressively refine image quality. The system repeatedly updates the reconstruction based on previously acquired images and new data, allowing convergence to high-quality results while managing computational complexity through controlled iteration steps and stopping criteria.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system applies partial reconstruction techniques where only certain image regions or frequency components are processed with full computational intensity. This selective approach maintains diagnostic quality in critical areas while reducing overall computational burden and processing time.

Inventive Principle:
Principle #16Partial or excessive action

3Measurement precision

If CT and MRI data are combined for simultaneous reconstruction, then image quality and diagnostic performance improve, but the computational burden and processing complexity increase

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent divides the combined CT-MRI reconstruction process into separate but coordinated segments. Each modality's data is processed through its own optimized reconstruction pipeline, with periodic synchronization and integration steps. This segmentation allows parallel computation of different data types while maintaining the benefits of combined information, thereby improving processing efficiency.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The reconstruction system is designed with universal algorithms that can handle both CT and MRI data types through a unified mathematical framework. This multi-functional approach allows the same computational engine to process different modalities without requiring completely separate processing chains, reducing overall computational burden and simplifying integration.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS11020077B2Simultaneous CT-MRI image reconstruction
Publication Date: 2021.06.01 RENESSELAER POLYTECHNIC INST
  • US11020077B2 patent drawing
  • US11020077B2 patent drawing
  • US11020077B2 patent drawing

AI summary

Novel and advantageous systems and method for obtaining and/or reconstructing simultaneous computed tomography (CT)-magnetic resonance imaging (MRI) images are provided. Structural coupling (SC) and compressive sensing (CS) techniques can be combined to unify and improve CT and MRI reconstruction. A bidirectional image estimation method can be used to connect images from different modalities, with CT and MRI data serving as prior knowledge to each other to produce better CT and MRI image quality than would be realized with individual reconstruction.