Cuirass Ventilator Pressure Control for COPD Dyspnea

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Solution Overview

Problem

Current treatments for dyspnea on exertion (DOE) in chronic obstructive pulmonary disease (COPD) and other respiratory disorders are not universally effective, as they fail to provide a comprehensive approach to assist breathing and alleviate dynamic hyperinflation.

Innovation Solution

A cuirass/ventilator device that includes a cuirass with a shell, sensors, a pressure creation means for applying negative or positive pressure, and a controller that adjusts pressure based on the patient's breathing pattern to assist in inhalation and exhalation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional treatments (supplemental oxygen, bronchodilators, corticosteroids) are used for COPD patients, then some symptom relief may be achieved, but the treatments fail to provide universal effectiveness and do not adequately address dynamic hyperinflation and work of respiratory muscles

Engineering Contradiction:
Improvetreatment effectivenessVSAvoiduniversal applicability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The cuirass/ventilator device dynamically adjusts pressure parameters (positive and negative pressure levels, duration, and timing) based on real-time sensor feedback from the patient's breathing pattern, allowing the treatment to adapt to individual patient needs and varying breathing conditions, thereby achieving both reliability and adaptability

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If a cuirass/ventilator device with real-time pressure adjustment is implemented, then breathing assistance is improved, but device complexity increases

Engineering Contradiction:
Improvebreathing assistance effectivenessVSAvoidsystem complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The device incorporates sensors that automatically detect the patient's breathing pattern and trigger mechanism that self-adjusts pressure delivery without requiring manual intervention or complex user programming, allowing the system to serve itself and simplify operation while maintaining effectiveness

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system uses sensors to continuously monitor breathing patterns and provides real-time feedback to the pressure creation means, enabling automatic adjustment of pressure parameters based on actual patient needs, which improves ease of operation while the automated feedback loop manages the complexity

Inventive Principle:
Principle #23Feedback

3Force

If pressure assistance is provided to match patient breathing pattern, then muscular effort is reduced, but measurement and control precision requirements increase

Engineering Contradiction:
Improverespiratory muscle effortVSAvoidbreathing pattern detection accuracy
Core Design Contradiction:
ForceVSMeasurement precision

Solution Approach 1:

The device replaces complex mechanical breathing analysis with electronic sensors and digital signal processing to detect and analyze breathing patterns, achieving high measurement precision while reducing the mechanical complexity of the control system

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively reduces the muscular effort required for breathing, improves breathing mechanics, and alleviates dyspnea on exertion by providing tailored pressure assistance that matches the patient's breathing pattern.

Implementation Method 1

a pressure creation means for providing at least one of a negative pressure or a positive pressure within the shell

Methodology Applied
Scientific EffectNegative pressure:

Implementation Method 2

a pressure creation means for providing at least one of a negative pressure or a positive pressure within the shell

Methodology Applied
Scientific EffectPositive pressure:

Implementation Method 3

The sensor is adapted to measure a breath pattern parameter corresponding to a patient's breathing pattern

Methodology Applied
Scientific EffectBreathing pattern detection:

Data Source

PatentUS12318348B2On ambulatory respiratory assist device
Publication Date: 2025.06.03 THE TRUSTEES OF THE UNIV OF PENNSYLVANIA
  • US12318348B2 patent drawing
  • US12318348B2 patent drawing
  • US12318348B2 patent drawing

AI summary

Provided herein is a device comprising a cuirass, which includes a shell, at least one sensor, a pressure creation means for providing at least one of a negative pressure or a positive pressure within the shell, and a controller operably connected to the pressure creation means, wherein the controller is adapted to receive an input signal from the at least one sensor and adapted to provide an output signal to the pressure creation means, and wherein the pressure creation means is adapted to provide a greater or lesser amount of pressure within the shell in response to the output signal. Also provided are methods of use.