3D Culture Device Liquid Pressure Volume Control
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Solution Overview
Problem
Conventional biological culture instruments face instability in controlling the volume of culture medium due to air compressibility, which is unsuitable for effective bioparticle culture.
Innovation Solution
A three-dimensional culture device with accommodating wells, a cover, and a driving mechanism, where the culture medium is filled in the wells and insertion pipes, allowing stable volume control through liquid-pressure management, ensuring bioparticles are immersed and biological information is transmitted effectively.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If air pressure regulation is used to control culture medium volume, then the culture instrument can accommodate culture medium, but the volume control becomes unstable due to air compressibility
Solution Approach 1:
The patent uses a liquid pressure transmission system instead of gas pressure. A liquid reservoir connects through liquid-filled channels to the culture chambers, providing incompressible pressure transmission for stable volume control while maintaining the ability to regulate culture medium levels
2Productivity
If conventional culture chambers are used, then bioparticles can be cultured, but the unstable volume control makes it unsuitable for effective bioparticle culture
Solution Approach 1:
The invention implements a liquid-based pressure regulation system where culture medium is transmitted from a reservoir through liquid-filled channels to the culture chambers. This provides stable, incompressible pressure control that maintains consistent culture environment for effective bioparticle cultivation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enables stable control of culture medium volume, enhancing the survival rate of bioparticles by maintaining a consistent environment and facilitating the transmission of biological information.
Implementation Method 1
The driving mechanism is configured to drive the culture medium in the cover so as to allow the culture medium to flow into or out of each of the culture spaces for controlling the volume of the culture medium in each of the culture spaces
Implementation Method 2
Each of the insertion pipes is in spatial communication with the corresponding culture space through the filtering bottom structure of the corresponding accommodating well
Data Source
AI summary
A three-dimensional culture device and a biological culture instrument are provided. The biological culture instrument is configured to receive a culture medium and includes a container, a cover, and a driving mechanism assembled to the cover. The container includes a plurality of accommodating wells each having a filtering bottom structure and a surrounding wall connected to the filtering bottom structure. Each of the surrounding walls defines a culture space for accommodating the culture medium and at least one bioparticle. The cover includes a communication portion and a plurality of insertion pipes being in spatial communication with the communication portion. Each of the insertion pipes is inserted into one of the accommodating wells, and is in spatial communication with the culture space through the filtering bottom structure. The driving mechanism is configured to control volume of the culture medium in each of the culture spaces through the cover.