Curcumin Composition for Cold Symptom Relief
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The effectiveness of curcumin preparations for relieving common cold symptoms is unclear, and existing cold remedies with multiple components raise concerns about side effects.
Innovation Solution
A randomized, placebo-controlled, double-blind study compared two curcumin preparations, finding that they reduce the incidence of common cold symptoms and are effective as symptom-relieving agents when containing fine particles of curcumin or turmeric pigment with a cellulose derivative, administered orally in doses of 90 mg to 300 mg per day.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cold remedies containing multiple components (non-steroidal anti-inflammatory agents, antihistamines, anticholinergic agents, etc.) are used, then various cold symptoms can be relieved, but side effects increase
Solution Approach 1:
The invention extracts and isolates curcumin as a single active ingredient from complex conventional cold remedies. By focusing on curcumin's anti-inflammatory activity and its ability to inhibit inflammatory cytokine release, the patent eliminates the need for multiple components (non-steroidal anti-inflammatory agents, antihistamines, anticholinergic agents) while maintaining symptom relief effectiveness and reducing side effects
Solution Approach 2:
The invention changes the chemical form of curcumin from conventional crystalline structures to fine particles with specific surface area characteristics (0.3 m²/g to 3.0 m²/g) and controls moisture content (5% to 15%) to optimize bioavailability and effectiveness. This parameter optimization allows curcumin to effectively relieve cold symptoms at lower doses, further reducing potential side effects
2Object-generated harmful factors
If curcumin is used to relieve common cold symptoms, then side effects are reduced, but the effectiveness for various cold symptoms is unclear
Solution Approach 1:
The invention performs preliminary characterization of curcumin's properties relevant to cold symptom relief, including anti-inflammatory activity, cytokine inhibition capability, and fine particle characteristics. By establishing these properties beforehand and defining specific particle parameters (surface area 0.3-3.0 m²/g, moisture content 5-15%), the patent creates a foundation for demonstrating effectiveness across various cold symptoms while maintaining safety
Solution Approach 2:
The invention positions curcumin as a multi-functional agent that can address various cold symptoms through its broad anti-inflammatory and cytokine-inhibiting properties. The patent suggests curcumin may be effective for multiple symptoms including nasal congestion, throat pain, cough, and body aches, making it a universal cold remedy that reduces side effects while maintaining broad effectiveness
Data Source
AI summary
To reveal which curcumin preparation, among various existing curcumin preparations, is effective for various symptoms of a common cold.Provided is an agent for relieving common cold symptom which contains, as an active ingredient, a curcumin-containing composition that contains fine particles of curcumin or turmeric pigment, or a mixture containing curcumin or turmeric pigment containing an amorphous thereof and a cellulose derivative.