Curved-Edge Tablet Design for Volume Retention and Anti-Sticking

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Solution Overview

Problem

Tablets designed to be longer in one direction face challenges in maintaining volume without increasing thickness, and suffer from sticking issues during film-coating treatments, leading to yield defects like 'twinning' where multiple tablets adhere together.

Innovation Solution

A tablet design with a side edge formed by a curve projecting outward, having a radius of curvature at least 1.5 times the tablet length, achieving a projected area ratio of at least 97% compared to a standard elliptical tablet, while preventing excessive curvature that could cause sticking during film-coating.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If the thickness of the tablet is increased to keep the volume large, then the volume is maintained, but the tablet becomes difficult to swallow

Engineering Contradiction:
Improvetablet volumeVSAvoidease of swallowing
Core Design Contradiction:
Volume of moving objectVSEase of operation

Solution Approach 1:

The patent applies curvature to the side edges of the tablet, forming them with a radius of curvature of at least 1.5 times the tablet length. This curved design increases the projected area ratio to at least 97% compared to standard elliptical tablets, allowing the tablet to maintain large volume while keeping the thickness within swallowable limits. The curved side edges optimize the volume-to-thickness ratio without compromising ease of swallowing.

Inventive Principle:
Principle #14Spheroidality (Curvature)

2Volume of moving object

If the projected area is increased to maintain volume without increasing thickness, then volume is retained, but the tablets stick together during film-coating treatment

Engineering Contradiction:
Improvetablet volumeVSAvoidtablet sticking
Core Design Contradiction:
Volume of moving objectVSObject-generated harmful factors

Solution Approach 1:

The patent changes the geometric parameters of the tablet by specifying a radius of curvature for the side edges that is at least 1.5 times the tablet length. This parameter change creates a projected area ratio of at least 97% while preventing the side edges from being excessively long and linear, thereby reducing tablet sticking during film-coating treatment and improving manufacturing yield.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If the side edge is made linear to simplify manufacturing, then manufacturing is easier, but tablets stick together during film-coating

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidtablet sticking
Core Design Contradiction:
Ease of manufactureVSObject-generated harmful factors

Solution Approach 1:

The patent replaces linear side edges with curved side edges having a radius of curvature of at least 1.5 times the tablet length. This curvature prevents the formation of long linear portions that cause tablets to stick together during film-coating, while still maintaining manufacturing feasibility through a well-defined geometric parameter.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Data Source

PatentEP1867324B1tablet
Publication Date: 2016.07.13 TAKEDA PHARMA CO LTD
  • EP1867324B1 patent drawingFigure 1~2
  • EP1867324B1 patent drawingFigure 3
  • EP1867324B1 patent drawingFigure 4(a)~4(c)

AI summary

The present invention can retain the volume of a tablet large without increasing the thickness of the tablet or the like dimension and prevents a plurality of tablets from sticking to each other even if they are subjected to a film-coating or the like treatment, so as to improve the yield. The tablet is a tablet (1) longer in one direction when seen in plan. The tablet (1) has side edges (6) each of which extends in a longitudinal direction and is formed in the shape of a curve projecting outwardly in plan view. The curve has a radius of curvature (R1) set to at least 1.5 times a length (L) of the tablet. This makes a projected area of the tablet (1) in plan view at least 97% with respect to a projected area of a standard elliptical tablet having opposite end portions each of which is formed by a semi-circle having a diameter of a width (W) of the tablet.