Custard Apple Peel Nanoparticle Synthesis via Ultrasonic Spray

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Solution Overview

Problem

Current methods for producing nanoparticles, such as chemical or mechanical techniques, are costly and can result in toxic byproducts, necessitating a more sustainable approach for synthesizing nanomaterials like custard apple peel nanoparticles.

Innovation Solution

Custard apple peel nanoparticles are synthesized by extracting custard apple peels in a solvent, spraying the extract into boiling water under ultrasonic conditions, sonicating, stirring, and drying to produce nanoparticles, which can then be mixed with a pharmaceutically acceptable carrier to create a pharmaceutical composition.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If chemical or mechanical methods are used to produce nanoparticles, then manufacturing capability is achieved, but production cost increases and toxic byproducts are generated

Engineering Contradiction:
Improvenanoparticle production capabilityVSAvoidtoxic byproducts
Core Design Contradiction:
Ease of manufactureVSObject-generated harmful factors

Solution Approach 1:

The patent uses plant extracts (containing phytochemicals) as an intermediary substance to facilitate nanoparticle synthesis. These natural compounds act as reducing agents and capping agents, enabling chemical reduction reactions without requiring harsh chemical reagents, thus producing nanoparticles without toxic byproducts while maintaining manufacturing capability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent employs inexpensive plant materials (agricultural waste or common plants) as sacrificial reducing agents. These organic materials are consumed in the reduction process, converting to harmless byproducts like CO2 and H2O, replacing expensive and persistent chemical reductants while eliminating toxic waste accumulation

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Ease of manufacture

If chemical or mechanical methods are used to produce nanoparticles, then manufacturing capability is achieved, but production cost increases

Engineering Contradiction:
Improvenanoparticle production capabilityVSAvoidproduction cost
Core Design Contradiction:
Ease of manufactureVSQuantity of substance

Solution Approach 1:

The patent utilizes low-cost plant materials, including agricultural waste products, as reducing agents and capping agents. These inexpensive organic materials replace costly chemical reagents and specialized equipment requirements, significantly reducing the overall production cost while maintaining effective nanoparticle synthesis capability

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent employs plant extracts that contain multiple functional components (reducing agents, capping agents, and stabilizing compounds) in a single natural product. This self-contained system eliminates the need for multiple separate chemical reagents and complex multi-step synthesis protocols, reducing both material costs and processing expenses

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method effectively produces custard apple peel nanoparticles with antimicrobial and antioxidant properties, as demonstrated by their ability to inhibit microbial growth and exhibit significant antioxidant activity, offering a sustainable alternative to traditional nanoparticle synthesis methods.

Implementation Method 1

spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Implementation Method 2

sonicating the mixture

Methodology Applied
Scientific EffectSonication: Ultrasound

Data Source

PatentUS10967020B2Method of synthesizing custard apple peel nanoparticles
Publication Date: 2021.04.06 KING SAUD UNIVERSITY
  • US10967020B2 patent drawing
  • US10967020B2 patent drawing
  • US10967020B2 patent drawing

AI summary

The custard apple peel nanoparticles may be manufactured by extracting custard apple peels in a solvent, spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture, sonicating the mixture, stirring the mixture, and drying the mixture to obtain custard apple peel nanoparticles. In an embodiment, the custard apple peel may be peel of Annona reticulata. In an embodiment, the custard apple peel nanoparticles may have improved antibacterial or antioxidant properties.