Customized Therapeutic Regimens Using Dosage Feedback

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Solution Overview

Problem

Standardized dosing regimens for prescription medications do not account for individual patient-specific factors such as other medications, implanted devices, or compliance, leading to sub-optimal treatment and potential side effects.

Innovation Solution

Development of patient-specific customized therapeutic regimens that adjust based on actual dosage administration data, including compliance and lifestyle information, using automated decision tools to recommend and implement changes in dosing schedules.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If standardized dosing regimens are used based on large patient population data, then treatment coverage is broad and easy to implement, but individual patient optimization is lost leading to sub-optimal treatment and side effects

Engineering Contradiction:
Improveindividual patient optimizationVSAvoidregimen complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent implements dynamic dosing regimens that automatically adjust medication doses based on real-time patient data from wearable sensors. The system transitions from static standardized dosing to dynamic personalized dosing by continuously monitoring physiological parameters and adjusting treatment protocols accordingly, resolving the contradiction between individual optimization and implementation complexity through automation

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system enables self-adjusting therapeutic regimens where the dosing protocol automatically modifies itself based on patient response data without requiring constant physician intervention. The automated decision tools and algorithms allow the treatment system to self-optimize for individual patients while maintaining simplicity of use through automated data collection and analysis

Inventive Principle:
Principle #25Self-service

2Reliability

If standardized dosing schedules are prescribed, then compliance monitoring is simplified, but patient-specific factors such as lifestyle, compliance patterns, and concurrent medications are not accounted for

Engineering Contradiction:
Improvetreatment efficacyVSAvoidcompliance monitoring
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent implements continuous feedback loops where wearable sensors monitor patient compliance and physiological responses in real-time. This feedback is fed into automated decision tools that adjust dosing regimens to maintain treatment efficacy while accounting for individual compliance patterns, resolving the contradiction between reliable treatment and ease of monitoring through automated feedback-driven adjustments

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system replaces manual compliance monitoring and physician judgment with automated sensor-based tracking and algorithmic decision-making. Wearable devices automatically track medication intake and physiological responses, substituting complex human monitoring processes with streamlined electronic systems that improve both reliability and ease of operation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If fixed dosing protocols are maintained, then treatment consistency is ensured, but ability to respond to changing patient conditions and non-compliance is reduced

Engineering Contradiction:
Improveresponse to patient changesVSAvoiddosing protocol stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent implements dynamic dosing protocols that automatically adapt to changing patient conditions while maintaining structured treatment frameworks. The system balances stability and adaptability by using automated algorithms to make controlled adjustments based on real-time data, allowing the protocol to evolve with patient needs while maintaining overall treatment consistency through systematic decision-making

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS11928614B2Patient customized therapeutic regimens
Publication Date: 2024.03.12 OTSUKA PHARM CO LTD
  • US11928614B2 patent drawing
  • US11928614B2 patent drawing
  • US11928614B2 patent drawing

AI summary

Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.