Corn Variety CV400433 Breeding for Predictable Hybrid Performance

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Solution Overview

Problem

Corn breeding aims to combine desirable traits like yield, disease resistance, and uniformity, but existing methods struggle to produce stable inbred plants with predictable performance due to genetic non-uniformity from cross-pollination, leading to unpredictable hybrid traits.

Innovation Solution

The development of the corn variety CV400433, which includes a cytoplasmic or nuclear factor for male sterility and genetic modifications such as single locus conversions for traits like herbicide tolerance and disease resistance, along with tissue cultures capable of regenerating plants with consistent morphological and physiological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If cross-pollination is used to combine desirable traits from different plants, then genetic diversity and trait combination are improved, but genetic non-uniformity increases leading to unpredictable hybrid performance

Engineering Contradiction:
Improvetrait combinationVSAvoidperformance predictability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The breeding process is divided into distinct stages: first developing homozygous inbred lines through repeated self-pollination, then crossing these stable lines to produce uniform F1 hybrids. This segmentation allows each stage to optimize for its specific goal - stability in inbreds, uniformity in hybrids.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Before creating hybrid plants, the patent performs preliminary self-pollination and selection over multiple generations to establish homozygous inbred parent lines. This preliminary action ensures that the parents are genetically stable and uniform, which then produces predictable uniform F1 hybrids when crossed.

Inventive Principle:
Principle #10Preliminary action

2Stability of the object's composition

If self-pollination is used to develop homozygous inbred plants, then genetic uniformity and breeding stability are improved, but loss of genetic diversity occurs

Engineering Contradiction:
Improvegenetic uniformityVSAvoidgenetic diversity
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The process discards the genetic diversity present in the original diverse population during self-pollination to achieve homozygosity, then recovers useful diversity by crossing different homozygous inbred lines. This allows the system to achieve uniformity when needed and diversity when needed through controlled processes.

Inventive Principle:
Principle #34Discarding and recovering

Solution Approach 2:

The patent performs preliminary self-pollination and selection over multiple generations to establish homozygous inbred parent lines with stable genetics. This preliminary action creates the uniform parents that will then be crossed to produce uniform F1 hybrids, ensuring predictability in the final hybrid performance.

Inventive Principle:
Principle #10Preliminary action

3Stability of the object's composition

If multiple generations of selfing and selection are performed to develop inbred plants, then homozygosity and uniformity are improved, but breeding time and complexity increase

Engineering Contradiction:
ImprovehomozygosityVSAvoidbreeding cycle duration
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent performs preliminary self-pollination and selection over multiple generations to establish homozygous inbred parent lines. This preliminary action, while time-consuming, creates stable parents that can then be crossed to produce uniform F1 hybrids, ensuring that the majority of the breeding time is invested in creating the stable foundation materials.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11382296B2Plants and seeds of corn variety CV400433
Publication Date: 2022.07.12 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the corn variety designated CV400433. The invention thus relates to the plants, seeds and tissue cultures of the variety CV400433, and to methods for producing a corn plant produced by crossing a corn plant of variety CV400433 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV400433 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV400433.