Corn Variety CV599858 Breeding via Segmented Inbred Lines

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Corn breeding aims to combine desirable traits like yield, disease resistance, and uniformity, but existing methods struggle to produce stable inbred plants with predictable performance due to genetic non-uniformity from cross-pollination, leading to unpredictable hybrid traits.

Innovation Solution

The development of the corn variety CV599858, which includes a cytoplasmic or nuclear factor for male sterility to prevent self-pollination, along with specific genetic loci for traits like herbicide tolerance and disease resistance, and the use of tissue cultures to regenerate plants with consistent physiological and morphological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If cross-pollination is used to combine genetic traits, then genetic diversity and trait combination are improved, but genetic uniformity and predictability deteriorate

Engineering Contradiction:
Improvegenetic diversityVSAvoidgenetic uniformity
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The breeding process is segmented into distinct phases: first developing uniform inbred lines through self-pollination, then using controlled cross-pollination only for hybrid production. This segmentation allows genetic diversity to be introduced only when needed, while maintaining uniformity during the critical inbred line development stage.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Inbred parental lines serve as intermediaries that carry specific genetic traits. These standardized intermediaries allow controlled combination of traits through deliberate crossing, rather than uncontrolled natural pollination, ensuring predictability in the hybrid offspring.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If self-pollination is used to develop inbred lines, then genetic uniformity is improved, but trait combination capability deteriorates

Engineering Contradiction:
Improvegenetic uniformityVSAvoidtrait combination
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

Self-pollination is used as a preliminary action to establish genetically uniform inbred lines before the actual trait combination occurs. This preliminary uniformity provides a stable foundation for subsequent controlled crossing, ensuring that when traits are combined in hybrids, the parental contributions are predictable and uniform.

Inventive Principle:
Principle #10Preliminary action

3Ease of manufacture

If natural pollination is used, then breeding simplicity is improved, but performance predictability deteriorates

Engineering Contradiction:
Improvebreeding simplicityVSAvoidperformance predictability
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

Inbred lines act as standardized intermediaries that simplify the breeding process by providing consistent, uniform parental material. This standardization maintains simplicity while dramatically improving predictability, as the uniform genetic background of inbreds ensures consistent hybrid performance.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The breeding approach changes the genetic parameter uniformity through self-pollination, creating inbreds with fixed genetic compositions. This parameter change transforms the breeding system from unpredictable natural variation to controlled, predictable inheritance patterns in hybrids.

Inventive Principle:
Principle #35Parameter changes

4Stability of the object's composition

If inbred lines are developed through multiple generations of selfing, then genetic stability is improved, but breeding time and complexity increase

Engineering Contradiction:
Improvegenetic stabilityVSAvoidbreeding time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

Instead of requiring complete homozygosity at all genetic loci, the program uses partial selfing for sufficient generations to achieve adequate uniformity for breeding purposes. This partial action approach achieves the necessary genetic stability without the excessive time required for complete homozygosity, allowing practical breeding timelines.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS8552278B2Plants and seeds of corn variety CV599858
Publication Date: 2013.10.08 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the corn variety designated CV599858. The invention thus relates to the plants, seeds and tissue cultures of the variety CV599858, and to methods for producing a corn plant produced by crossing a corn plant of variety CV599858 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV599858 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV599858.