Cyclic Amine Compounds for Enhanced Pesticidal Efficacy
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Solution Overview
Problem
Current pesticidally active compounds for controlling animal pests, particularly insects and arthropods, have limitations in efficacy and specificity, necessitating the development of novel cyclic amine compounds with improved pest control properties.
Innovation Solution
The development of novel cyclic amine compounds, specifically azetidinyl-, pyrrolidinyl-, piperidinyl-, and piperazinyl-pyridinyl carbonyl compounds with specific functional groups, which can form salts and N-oxides, offering enhanced pesticidal activity through targeted chemical structures.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current pesticidally active compounds are used for controlling animal pests, then pest control is achieved, but efficacy and specificity are limited
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of pesticidal compounds through systematic variation of substituents at different positions (R1-R6, R8-R11) and cyclic amine components (p1-p2, q1-q2). This structural parameter optimization enhances both efficacy against target pests and specificity by creating compounds with tailored molecular properties that selectively interact with pest biological systems while minimizing non-target effects.
2Reliability
If novel cyclic amine compounds with specific structural features are developed, then insecticidal and acaricidal properties are enhanced, but compound complexity increases
Solution Approach 1:
The patent employs segmentation by dividing the pesticidal compound into distinct functional modules: a core pyridinyl carbonyl structure, variable substituent groups (R1-R6, R8-R11), and cyclic amine components (azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl). This modular segmentation allows systematic optimization of insecticidal activity through targeted modification of specific segments while maintaining the overall molecular framework, thereby enhancing activity without proportionally increasing complexity.
Solution Approach 2:
The patent applies universality by designing a core molecular structure with multiple substitutable positions that can accommodate various functional groups and cyclic amine variants. This universal framework enables a single compound design to achieve multiple pesticidal functions (insecticidal, acaricidal activities) and target different pest types, reducing the need for entirely separate compound designs for different applications.
Data Source
AI summary
Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.