Synergistic Cyclic Ketoenol and Anthranilamide Combinations

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Solution Overview

Problem

Existing combinations of cyclic ketoenols and other insecticidally active compounds often exhibit unsatisfactory activity at low application rates, and mixtures of phthalamides and bioactive compounds do not always achieve optimal insecticidal and acaricidal efficacy.

Innovation Solution

The use of specific combinations of compounds of formula (I) and anthranilamides of formula (II), which show a synergistic effect, providing enhanced insecticidal and acaricidal activity beyond the sum of individual activities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If cyclic ketoenols and other insecticidally active compounds are used at low application rates, then cost and environmental impact are reduced, but insecticidal and acaricidal activity becomes unsatisfactory

Engineering Contradiction:
Improveapplication rateVSAvoidinsecticidal and acaricidal activity
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The patent combines cyclic ketoenols (formula I) with anthranilamides (formula II) to create a synergistic mixture that achieves superior insecticidal and acaricidal activity at lower application rates compared to individual compounds. This merging of two active substances resolves the contradiction by enabling effective pest control at reduced quantities through synergistic interaction.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite active substance system by combining cyclic ketoenols with anthranilamides in specific ratios. This composite approach allows the mixture to exhibit enhanced biological activity that exceeds the sum of individual components, enabling effective pest control at lower application rates.

Inventive Principle:
Principle #40Composite materials

2Reliability

If mixtures of phthalamides and bioactive compounds are used, then insecticidal and acaricidal action is achieved, but activity is not always optimal

Engineering Contradiction:
Improveinsecticidal and acaricidal actionVSAvoidactivity level
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent optimizes the composition parameters by specifying precise ratios of cyclic ketoenol to anthranilamide in the mixture. This parameter optimization ensures that the synergistic effect is maximized, achieving optimal insecticidal and acaricidal activity that exceeds previous formulations.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If known insecticidal compounds such as heterocycles, organotin compounds, benzoylureas and pyrethroids are used, then insecticidal and acaricidal properties are achieved, but activity is not always satisfactory

Engineering Contradiction:
Improveinsecticidal and acaricidal propertiesVSAvoidactivity level
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent employs anthranilamides as intermediary substances that synergistically enhance the activity of cyclic ketoenols. This intermediary approach creates a cooperative interaction between the two compounds, resulting in superior insecticidal and acaricidal activity compared to using either compound alone or with other known insecticides.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS8821898B2Active compound combinations having insecticidal and acaricidal properties
Publication Date: 2014.09.02 BAYER CROPSCIENCE AG
  • US8821898B2 patent drawing
  • US8821898B2 patent drawing
  • US8821898B2 patent drawing

AI summary

The invention relates to novel insecticidal active compound combinations comprising, firstly, cyclic ketoenols or other insecticidally active compounds and, secondly, further insecticidally active compounds from the group of the anthranilamides, which combinations are highly suitable for controlling animal pests, such as insects and unwanted acarides.