Cycloalkyl Diamine Compounds for Cancer Treatment
Solution Overview
Problem
Current cancer treatments, particularly chemotherapy, often face challenges in efficacy and tolerability, necessitating the development of safer and more effective anti-carcinoma drugs due to the high morbidity and mortality rates associated with cancer and the increasing financial burden.
Innovation Solution
The use of novel cycloalkyl-diamines and their pharmaceutical compositions, specifically compounds of formula I, which inhibit cancer cell growth by administering a compound of formula I or its pharmaceutically effective salts, effectively targeting cancer cells and carcinomas in mammals, including humans.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional chemotherapeutic agents are used to treat cancer, then cancer cell growth is inhibited, but tolerability and safety deteriorate due to high morbidity and mortality rates
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of chemotherapeutic agents through specific cycloalkyl-diamine compounds with defined molecular formulas (I, II, III). These structural parameter changes result in compounds that maintain anti-cancer efficacy while improving safety profiles and reducing toxic side effects compared to conventional chemotherapy agents
2Reliability
If conventional chemotherapeutic agents are used to treat cancer, then cancer cell growth is inhibited, but safety deteriorates due to high morbidity and mortality rates
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of chemotherapeutic agents through specific cycloalkyl-diamine compounds with defined molecular formulas (I, II, III). These structural parameter changes result in compounds that maintain anti-cancer efficacy while improving safety profiles and reducing toxic side effects compared to conventional chemotherapy agents
Data Source
AI summary
The invention is directed to a method of treatment of a cancer, in a mammal, the method comprising administering to said mammal in need of such treatment an effective amount of a cell growth inhibitory compound of formula I or a pharmaceutically acceptable salt form thereof.