Cyclodextrin-Loaded Colloidal Mineral Solution for Stable Delivery
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Solution Overview
Problem
There is a strong need for new formulations that can deliver trace elements from Plant Mineral Toddy solution in a stable manner, enhancing their bioavailability.
Innovation Solution
A formulation comprising an atomized vegetable colloidal solution loaded onto cyclodextrins, specifically alpha-cyclodextrin, beta-cyclodextrin, or their derivatives, which maintains the mineral components' stability and bioavailability, suitable for use in food and cosmetic products.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If trace elements are delivered in conventional formulations, then mineral content is provided, but stability and bioavailability are insufficient
Solution Approach 1:
The patent applies the nesting principle by placing mineral ions (Ca2+, Mg2+, K+, Na+, Fe2+/3+, Zn2+, Cu2+, Mn2+, Se2-) inside the hollow cavity of cyclodextrin molecules. The cyclodextrin acts as a host structure that encapsulates the mineral guests, creating a stable inclusion complex that protects the minerals while enabling controlled release and improved bioavailability.
Solution Approach 2:
The cyclodextrin serves as an intermediary carrier between the mineral sources (Planta Mineral Toddy solution) and the biological system. It mediates the delivery by forming stable complexes with mineral ions, protecting them from degradation while facilitating their absorption and transport in the body.
2Quantity of substance
If mineral concentration is increased in formulations, then nutrient content is improved, but stability deteriorates
Solution Approach 1:
High concentrations of mineral ions are stabilized by nesting them within cyclodextrin cavities. The host-guest inclusion complexes prevent mineral precipitation, oxidation, and interactions that would otherwise cause formulation instability, enabling high mineral content while maintaining stability.
Solution Approach 2:
The patent creates a composite system combining organic cyclodextrin molecules with inorganic mineral ions. This composite approach allows the formulation to simultaneously achieve high mineral concentration and stability, as the cyclodextrin matrix provides structural integrity while accommodating multiple mineral species.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The cyclodextrin-loaded formulation provides a stable and controlled release of minerals, ensuring their effective delivery in food supplements, cosmetic products, and mineral replenisher beverages, while maintaining skin tonicity in cosmetic applications.
Implementation Method 1
The cavity of cyclodextrins can host various molecules depending on their chemical-physical characteristics... cyclodextrins are used in pharmaceutical technology to increase the water solubility of molecules through the formation of inclusion complexes
Implementation Method 2
A formulation which comprises an atomized vegetable colloidal solution loaded on cyclodextrins
Data Source
AI summary
The present invention relates to a formulation which comprises an atomized vegetable colloidal solution loaded on cyclodextrins, wherein said colloidal solution comprises calcium, chlorine, phosphorus, magnesium, potassium, sodium and, optionally, iron, manganese, zinc, copper and / or selenium. Compositions comprising said formulation and their use form a further object of the present invention.