Cyclodextrin Pheromone Dispersion Sustained Release

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Solution Overview

Problem

Conventional spray-type sex pheromone sustained release preparations experience rapid initial release of the pheromone substance, leading to a short effective release period, making them impractical for large-area agricultural applications, and they contribute to environmental pollution due to synthetic polymer bases.

Innovation Solution

A water dispersion type sex pheromone sustained release preparation using an insect sex pheromone substance enclosed in a cyclodextrin ring, combined with a non-inclusion cyclodextrin and a water-soluble polymer in a water solvent, which controls the initial release and extends the effective release period.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a cyclodextrin powder enclosing an insect sex pheromone substance is dispersed in water for spraying, then the pheromone substance can be delivered to agricultural fields, but strikingly quick initial release occurs causing about half of the content to be released immediately, resulting in extremely short effective release period

Engineering Contradiction:
Improvedelivery efficiencyVSAvoideffective release period
Core Design Contradiction:
ProductivityVSDuration of action of moving object

Solution Approach 1:

The patent introduces a water-soluble polymer as an intermediary substance that forms a protective matrix around the cyclodextrin-pheromone complexes. This polymer matrix acts as a barrier that controls the release rate, preventing the rapid initial release observed in pure cyclodextrin dispersions while maintaining the ability to deliver pheromone to the target area. The polymer serves as a mediating layer between the pheromone source and the environment.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite system combining cyclodextrin (for pheromone enclosure), water-soluble polymer (for matrix formation and release control), and water (as solvent). This composite material approach allows the formulation to simultaneously achieve good dispersibility, controlled release kinetics, and practical application characteristics. The synergistic combination resolves the contradiction between rapid delivery and sustained release duration.

Inventive Principle:
Principle #40Composite materials

2Duration of action of stationary object

If conventional spray-type preparations use synthetic polymer bases for sustained release, then the pheromone can be released over time, but the preparations remain without being decomposed by microorganisms and put a load on the natural world

Engineering Contradiction:
Improvesustained release durationVSAvoidenvironmental pollution
Core Design Contradiction:
Duration of action of stationary objectVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical composition parameter by replacing synthetic polymers with natural, water-soluble polymers in the formulation. This parameter change maintains the sustained release function through the natural polymer matrix while eliminating the environmental harm associated with non-biodegradable synthetic materials. The natural polymer decomposes readily through microbial action, resolving the contradiction between sustained release and environmental compatibility.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If several hundreds to a thousand of the preparations are placed per hectar on crops or structures, then the pheromone release coverage is sufficient, but it is substantially difficult to place the preparations in large-area agricultural fields or vast forests

Engineering Contradiction:
Improvepheromone release coverageVSAvoidplacement feasibility
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent employs spray technology, utilizing pneumatic and hydraulic principles to deliver the pheromone formulation throughout the agricultural field. The spray system can be operated from airplanes, helicopters, tractors, or speed sprayers, enabling widespread and uniform distribution of the pheromone preparation over large areas. This mechanical delivery method replaces the manual placement of individual preparations, making large-scale application feasible and reliable.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The preparation suppresses initial excess release, maintains a constant pheromone release for a predetermined period, and can be sprayed using a common sprayer, improving practicality and reducing environmental impact by using biodegradable components.

Implementation Method 1

a water dispersion type sex pheromone sustained release spray preparation, comprising insect sex pheromone substance which is enclosed in a ring of a cyclodextrin, an inclusion cyclodextrin which encloses the insect sex pheromone substance

Methodology Applied
Scientific EffectInclusion complex formation:

Implementation Method 2

a non-inclusion cyclodextrin which does not enclose the insect sex pheromone substance, a water-soluble polymer, and water

Methodology Applied
Scientific EffectDissolution: Solvation

Data Source

PatentEP2580960B1Water dispersion type sex pheromone sustained release preparation
Publication Date: 2018.08.15 SHIN ETSU CHEMICAL CO LTD
  • EP2580960B1 patent drawingFigure 1~2
  • EP2580960B1 patent drawingFigure 3~4
  • EP2580960B1 patent drawing

AI summary

Provided is a water dispersion type sex pheromone sustained release preparation which makes it possible to suppress excess release at the initial stage of spraying and release a sex pheromone substance at a constant amount for a predetermined period, and which can be sprayed by using a common sprayer. Specifically provided is a water dispersion type sex pheromone sustained release preparation, comprising an insect sex pheromone substance which is enclosed in a ring of a cyclodextrin, an inclusion cyclodextrin which encloses the insect sex pheromone substance, a non-inclusion cyclodextrin which does not enclose the insect sex pheromone substance, a water-soluble polymer, and water. Furthermore, provided is a method for producing a water dispersion type sex pheromone sustained release preparation, comprising at least a step of mixing an aqueous suspension of an insect sex pheromone substance which is enclosed by a cyclodextrin, with a non-inclusion cyclodextrin which does not enclose the insect sex pheromone substance, and a water-soluble polymer.