Cyclohexane and Cyclohexene Esters as Fragrance Boosters for Lower Dosage
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Solution Overview
Problem
The perfume industry faces challenges in creating fragrances that provide consistent odor profiles with secondary beneficial properties, such as solubility, stability, and safety, while also enhancing or masking unpleasant odors, and require high dosages to achieve desired effects.
Innovation Solution
The use of cyclohexane and/or cyclohexene esters, represented by compounds of Formula I, which possess unique olfactory properties like cinnamon, marzipan, fruity, and floral notes, can enhance and modify fragrance compositions, acting as boosters or amplifiers, improving stability and solubility, and reducing dosage requirements.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If high dosages of fragrance compositions are used to achieve desired odor results, then the odor effect is improved, but the complexity of the composition and potential harmful effects increase
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of fragrance components through specific ester formations (cyclohexane and cyclohexene esters with general formula I). This structural modification enables achieving desired odor effects at lower dosages while maintaining or improving safety profiles, thus resolving the contradiction between dosage quantity and harmful effects
Solution Approach 2:
The patent employs composite materials by creating fragrance compositions that combine multiple ester compounds of formula I with other fragrance ingredients. These composite fragrance systems synergistically enhance odor effects at reduced dosages, thereby addressing the contradiction between achieving desired odor results and minimizing harmful effects
2Reliability
If fragrance compositions are designed to provide consistent odor profiles, then the odor quality is improved, but the solubility and stability may deteriorate
Solution Approach 1:
The patent utilizes parameter changes by systematically varying the R groups in the ester general formula I (where R can be alkyl, alkenyl, cycloalkyl, or aryl with specific carbon chain lengths). This structural parameter optimization ensures consistent odor profiles while simultaneously improving solubility and storage stability characteristics of the fragrance compositions
3Adaptability or versatility
If new fragrance structures are selected from an almost unlimited number of possible structures, then the odor profile customization is improved, but the difficulty of selection and development increases
Solution Approach 1:
The patent applies segmentation by dividing the vast space of possible fragrance structures into a focused series of ester compounds following general formula I. This segmentation approach categorizes fragrance molecules by their core cyclohexane or cyclohexene structure with variable R groups, making the selection and development process more manageable while maintaining high odor profile customization capability
Solution Approach 2:
The patent implements universality by designing a family of ester compounds (general formula I) that can serve multiple fragrance functions. By varying the R groups within this universal structural framework, diverse odor profiles can be achieved from a single core structure, reducing selection complexity while maintaining versatility
4Reliability
If fragrance compositions are designed to enhance positive odor aspects and mask unpleasant aspects, then the overall fragrance quality is improved, but the required dosage increases
Solution Approach 1:
The patent applies the intermediary principle by using specific ester compounds of formula I as mediator substances that harmonize multiple fragrance ingredients. These mediator esters enhance positive odor aspects and mask unpleasant aspects through synergistic interactions, achieving high fragrance quality at reduced dosages by facilitating efficient odor blending and enhancement
Data Source
AI summary
Suggested is the use of at least one compound of Formula I as a fragrance.