Cyclopentanol Compounds for Complex Fragrance Profiles

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Solution Overview

Problem

The fragrance industry faces challenges in predicting the sensory activities of chemical structures, making it difficult to identify desirable fragrance chemicals for creating new perfumes and personal care products, as small differences in chemical structures can result in significant variations in odor profiles.

Innovation Solution

The development of novel cyclopentanols represented by specific formulas, which can be used to enhance, improve, or modify fragrances in perfumes, colognes, and personal care products, offering powerful and complex fragrance effects such as fresh, citrusy, and green notes with woodiness and earthy undertones.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If small differences in chemical structures are made, then odor profiles vary significantly, but it becomes difficult to predict sensory activities

Engineering Contradiction:
Improveodor profile variationVSAvoidprediction of sensory activities
Core Design Contradiction:
Adaptability or versatilityVSDifficulty of detecting and measuring

Solution Approach 1:

The patent systematically varies specific structural parameters of cyclopentanol compounds (substituent types, positions, and configurations) to achieve desired odor profiles. By changing R1 and R2 groups in Formula I, R3 and R4 in Formula II, and R5 and R6 in Formula III, the invention creates predictable structure-odor relationships that resolve the unpredictability issue while maintaining versatile fragrance characteristics

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If novel chemical structures are developed to create new fragrances, then fragrance diversity is improved, but identification of desirable fragrance chemicals becomes more challenging

Engineering Contradiction:
Improvefragrance diversityVSAvoididentification of desirable fragrance chemicals
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The patent divides the fragrance development process into systematic segments: (1) defining specific cyclopentanol core structures, (2) systematically varying substituent groups (R1-R6) according to defined formulas, (3) evaluating sensory properties of each variant. This segmented approach transforms the challenging task of identifying desirable fragrance chemicals into a structured process with predictable outcomes

Inventive Principle:
Principle #1Segmentation

3Reliability

If cyclopentanols with specific structures are used to enhance fragrance, then fragrance performance is improved, but complexity of chemical structure increases

Engineering Contradiction:
Improvefragrance performanceVSAvoidchemical structure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies local quality by introducing specific substituents (R1-R6 groups) at particular positions on the cyclopentanol core structure. Each substituent location and type is carefully selected to provide specific fragrance characteristics (fresh, citrusy, green notes with woodiness and earthy undertones) while maintaining overall structural manageability through the defined formulaic framework

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS9701925B2Cyclopentanol compounds
Publication Date: 2017.07.11 INTERNATIONAL FLAVORS & FRAGRANCES INC
  • US9701925B2 patent drawing
  • US9701925B2 patent drawing
  • US9701925B2 patent drawing

AI summary

The present invention pertains to novel cyclopentanols and their unexpected advantageous use thereof in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet waters, fabric care products, personal products, and the like.