Demineralized Bone Fiber Composition for Low-Binding Cannula Delivery
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Solution Overview
Problem
Current bone graft materials face challenges in being delivered through narrow cannulae due to binding issues, which complicates surgical procedures and increases costs and risks of patient injury.
Innovation Solution
The development of demineralized bone fibers (DBF) that are processed into cohesive forms, such as pellets or bags, with controlled geometry and surface hardening to prevent binding, allowing for efficient delivery through long, small-diameter cannulae.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If bone graft materials are delivered through narrow cannulae, then minimally invasive surgery is achieved, but binding issues occur that complicate procedures
Solution Approach 1:
The bone graft material undergoes parameter changes in its physical properties through demineralization and fiber formation, transforming from hard cortical bone to flexible demineralized bone fibers that can be delivered through narrow cannulae without binding, while maintaining osteoinductive and osteoconductive properties
Solution Approach 2:
The invention creates a composite material structure by combining demineralized bone fibers with specific geometric configurations and surface treatments, resulting in a material that exhibits both flexibility for cannulae delivery and structural integrity for effective bone grafting
2Reliability
If autograft bone is used as gold standard, then bone healing is optimized, but additional surgical trauma and patient morbidity occur
Solution Approach 1:
The invention creates a copy of the essential functional properties of autograft bone by processing allograft cortical bone into demineralized bone fibers that replicate the osteoinductive and osteoconductive capabilities of autograft, eliminating the need for additional harvesting surgery while achieving comparable bone healing outcomes
3Ease of operation
If bone graft materials are made cohesive for delivery, then delivery through cannulae is improved, but binding issues may occur
Solution Approach 1:
The bone graft material exhibits local quality variations with different surface characteristics - the exterior surface is treated to reduce friction and prevent binding during cannulae delivery, while the interior structure maintains porosity and cohesion for effective bone healing and integration
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient and safe delivery of bone grafts to deep body sites with minimal surgical trauma, ensuring complete filling of defects and reducing procedural complications.
Implementation Method 1
The cylinder may have an outermost layer that is annealed by heating and/or dehydrothermal treatment
Implementation Method 2
The cylinder may have an outermost layer that is annealed by heating and/or dehydrothermal treatment
Data Source
AI summary
A bone implant composition and methods thereof include bone material made into various implant shapes including a cylinder having an outermost layer and an inner layer completely surrounded by the outermost layer. The bone implant compositions and methods include a bag or cylindrical tube made from a bone material which may be filled with additional bone material.