Deconvolution-Based Treatment Validation for Refractive Surgery
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Solution Overview
Problem
Current refractive surgical techniques face challenges in accurately assessing and validating treatments, particularly in minimizing post-operative induction of high-order aberrations such as spherical aberration, which can lead to regression and vision issues in patients with high myopia and hyperopia.
Innovation Solution
The development of systems and methods that include deconvolution techniques based on a cornea smoothing model to generate a modified ablation target that minimizes post-operative spherical aberration, using spatial domain kernel filters and low-pass filters to adjust the original target profile, ensuring the treatment shape induces little to no spherical aberration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional laser ablation treatment is applied to correct refractive errors, then vision correction is achieved, but post-operative spherical aberration is induced leading to regression and vision issues
Solution Approach 1:
The patent applies preliminary anti-action by modifying the ablation target profile beforehand to counteract the expected epithelial smoothing effect. The deconvolution process pre-compensates for the corneal remodeling that will occur post-surgery, creating a treatment profile that induces minimal spherical aberration after the epithelium heals. This resolves the contradiction by preventing the harmful spherical aberration before it occurs, while maintaining effective refractive correction.
Solution Approach 2:
The patent changes the parameters of the ablation target profile through deconvolution processing. By applying spatial domain kernel filters and low-pass filters, the original target profile is transformed into a modified profile with altered curvature and depth characteristics. This parameter modification enables the treatment to achieve vision correction while minimizing post-operative spherical aberration induction.
2Manufacturing precision
If ablation depth is increased to treat high myopia andhyperopia, then refractive error correction is improved, but induced spherical aberration increases leading to regression
Solution Approach 1:
The patent applies local quality by creating non-uniform modifications to different regions of the ablation profile. The deconvolution process selectively adjusts the curvature and depth in specific zones of the cornea, particularly at the periphery where epithelial smoothing has the greatest impact on spherical aberration. This localized optimization allows deep ablation for high refractive errors while minimizing aberration induction in critical areas.
3Stability of the object's composition
If epithelial smoothing is allowed to occur naturally after surgery, then corneal healing is achieved, but regression and high-order aberrations occur
Solution Approach 1:
The patent performs preliminary action by pre-calculating and pre-compensating for the epithelial smoothing effect before surgery. The deconvolution process anticipates the natural healing process and adjusts the ablation profile in advance to counteract the smoothing effect. This ensures that when epithelial smoothing occurs during normal healing, the resulting corneal shape maintains the intended refractive correction with minimal spherical aberration, preventing regression.
Data Source
AI summary
Treatment validation techniques include generating a modified treatment target from an original treatment target using a modification process, and comparing induced aberrations provided by the original and modified treatment targets, so as to verify the modified treatment target or the modification process. In some cases, a modification process may include a deconvolution process, a low pass filter process, a scaling process, or an adjustment process. The induced aberrations may include high order aberrations, such as spherical aberration.