Deep Learning Chromosome Recognition via ResNet and MLP
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Solution Overview
Problem
Current chromosome recognition methods rely on manual operations and artificial recognition, which are time-consuming, subjective, and of low accuracy, making them inefficient and prone to external interference, especially in the context of high prevalence of chromosome diseases in China.
Innovation Solution
A deep learning-based chromosome recognition method that involves obtaining independent chromosome images, calculating manual features, performing image processing, building a deep learning model using ResNet and MLP classifiers, and predicting chromosome types with high accuracy, thereby reducing doctor workload and external interference.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If manual operations and artificial recognition are used for chromosome analysis, then doctors can recognize chromosome types based on their expertise, but the examination time is extended to two weeks or longer and the workload is heavier
Solution Approach 1:
The patent replaces the manual mechanical recognition process with an automated deep learning system. The deep learning model automatically extracts features from chromosome images and classifies chromosome types, substituting the doctor's manual visual inspection and decision-making process. This automation dramatically reduces examination time from two weeks or longer to a much shorter automated processing time while maintaining high recognition accuracy through the model's learned patterns from training data.
2Measurement precision
If manual chromosome recognition is performed by experienced doctors, then recognition can be done with expertise, but the process is strongly subjective and easily influenced by external environment
Solution Approach 1:
The deep learning model achieves self-service by automatically learning chromosome recognition patterns from training data without requiring subjective human judgment. The model consistently applies the same learned features and classification rules to all chromosome images, eliminating variability caused by different doctors' expertise levels, fatigue, or external environmental influences. This self-service automation ensures reliable and consistent recognition results across different cases and time periods.
3Productivity
If deep learning method is adopted for automatic chromosome recognition, then recognition efficiency is improved and workload is reduced, but the system requires building complex deep learning models
Solution Approach 1:
The patent applies preliminary action by pre-training the deep learning model on a large dataset of chromosome images before deployment. The model learns chromosome features, patterns, and classification rules in advance during the training phase. When deployed for actual chromosome analysis, the pre-trained model can quickly and accurately recognize chromosome types without requiring complex real-time processing or manual intervention, thus improving productivity while the one-time training complexity is amortized over many subsequent efficient inferences.
Data Source
AI summary
A chromosome recognition method based on deep learning includes the following steps: step 1, obtaining an independent chromosome image; step 2, calculating a manual feature of a chromosome; step 3, performing basic image processing on the chromosome; step 4, building a deep learning model; and step 5, predicting a type of the chromosome based on the deep learning model. By adopting a deep learning method, the chromosome recognition method can be used for recognizing the chromosome type accurately and efficiently. Compared with an existing recognition technology, the chromosome recognition method based on deep learning of the present invention has the advantages that the chromosome karyotype analysis efficiency can be effectively improved, the recognition sequencing time can be shortened, automatic classification and sequencing of chromosomes can be completely with high accuracy.


