Deep Learning Contrast Flow Modeling for CT Scan Timing
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Solution Overview
Problem
Existing contrast-enhanced CT scans rely on anecdotal medical practice and additional monitoring scans, leading to increased radiation dose and contrast load without ensuring optimal image quality.
Innovation Solution
Utilize deep learning models to predict contrast enhancement events based on patient demographics and clinical information, allowing for confident timing of diagnostic scans without direct monitoring, thereby reducing radiation and contrast usage while maintaining image quality.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If contrast flow is monitored using multiple sampling scans, then the timing accuracy for diagnostic scanning is improved, but the radiation dose and contrast load increase
Solution Approach 1:
The patent uses deep learning models to create a virtual copy or simulation of contrast flow dynamics based on patient demographics and clinical information. Instead of physically monitoring contrast flow through multiple sampling scans, the system generates a predictive model that replicates contrast behavior, allowing accurate timing prediction without the harmful radiation exposure from repeated scanning.
Solution Approach 2:
The patent replaces the mechanical/physical system of repeated CT scanning for contrast flow monitoring with an information-processing system using deep learning algorithms. The neural network processes patient data and clinical parameters to predict contrast enhancement timing, substituting physical measurement with computational prediction to eliminate additional radiation exposure.
2Reliability
If multiple monitoring scans are performed to determine optimal scan timing, then the diagnostic image quality is improved, but the contrast load and radiation dose increase
Solution Approach 1:
The deep learning model creates a virtual representation of contrast flow dynamics, allowing the system to predict optimal scan timing without physically administering multiple contrast doses. The model learns from training data to simulate contrast behavior, providing reliable timing predictions while using minimal or no contrast media in the actual diagnostic procedure.
Solution Approach 2:
The system performs preliminary learning from training data to establish contrast flow patterns before the actual diagnostic scan. By pre-training the deep learning model on contrast dynamics, the system can make accurate predictions about when contrast enhancement will occur, allowing the diagnostic scan to be timed correctly without needing multiple monitoring scans or additional contrast doses.
3Object-affected harmful factors
If deep learning models are used to predict contrast enhancement timing, then the radiation dose is reduced, but the system complexity increases
Solution Approach 1:
The deep learning model acts as an intermediary between patient data and diagnostic scan timing decisions. Instead of directly using complex real-time contrast flow monitoring systems, the patent introduces a trained neural network as a mediator that processes patient demographics and clinical information to predict timing, simplifying the overall system architecture while reducing radiation exposure.
Solution Approach 2:
The deep learning model is pre-trained using historical data and contrast flow patterns, allowing it to autonomously make timing predictions without requiring complex real-time monitoring infrastructure. The model serves itself by using its trained parameters to directly output predictive timing based on input data, reducing the need for complex additional hardware or monitoring systems.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Accurately predicts contrast enhancement times with high confidence, reducing radiation dose and contrast load while ensuring improved image quality in CT scans.
Implementation Method 1
estimating a time to perform a diagnostic scan of a patient based on demographics of the patient
Implementation Method 2
technologies such as computed tomography (CT) use various physical principles, such as the differential transmission of x-rays through the target volume
Implementation Method 3
a detector that receives the x-rays attenuated by the subject
Data Source
AI summary
Systems and methods are provided for contrast-enhanced diagnostic imaging. In one aspect, a system includes an x-ray source; a detector; a data acquisition system (DAS) operably connected to the detector; and a computing device operably connected to the DAS and configured with instructions that when executed cause the computing device generate a first estimated time to perform a diagnostic scan; determine a first confidence level of the first estimated time; control the x-ray source and the detector to perform the diagnostic scan of the subject at the first estimated time in response to a first confidence level being above a threshold; and generate a second estimated time to perform the diagnostic scan and a second confidence level of the second estimated time in response to the first confidence level of the first estimated time being below a threshold.


