Deep Learning Hematoma Expansion Prediction via CT Analysis

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Solution Overview

Problem

Current methods for predicting hematoma expansion in intracerebral hemorrhage (ICH) are inaccurate, hindering the development of effective interventions and posing risks to patients due to the inability to precisely identify those who would benefit from treatments aimed at reducing hematoma expansion.

Innovation Solution

A deep learning algorithm is employed to analyze diagnostic CT scans, utilizing convolutional neural networks to identify patients at risk for hematoma expansion by recognizing features such as hypodensities and irregular shapes, thereby enabling targeted interventions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional methods are used to predict hematoma expansion, then the process is simple, but the prediction accuracy is low

Engineering Contradiction:
Improveprediction accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces traditional mechanical/visual assessment methods with an automated deep learning system that uses convolutional neural networks to analyze CT images. This substitution enables high-accuracy prediction of hematoma expansion by automatically extracting imaging features and patterns that are imperceptible to human observers, thereby resolving the contradiction between prediction accuracy and system complexity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces a deep learning algorithm as an intermediary between the CT images and the prediction outcome. This intermediary automatically processes the imaging data, extracts relevant features, and generates predictions, eliminating the need for complex manual assessment while achieving high accuracy through automated feature extraction and pattern recognition.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If deep learning analysis is implemented, then prediction accuracy improves, but processing time increases

Engineering Contradiction:
Improveprediction accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary actions by pre-training the deep learning model on large datasets and pre-processing the CT images into standardized formats before actual prediction. This preparation work is done in advance, allowing the model to quickly process new cases without sacrificing accuracy, thereby reducing the time loss during critical clinical decision-making.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent optimizes processing time by adjusting parameters such as image resolution, network depth, and batch size to find the optimal balance between accuracy and speed. By changing these parameters, the system achieves high prediction accuracy while maintaining processing speeds suitable for clinical workflows.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If manual assessment methods are used, then the system is easy to operate, but the precision of identifying patients is low

Engineering Contradiction:
Improvepatient identification precisionVSAvoidoperational simplicity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent implements self-service by enabling the deep learning system to automatically perform the entire assessment process without requiring manual intervention. The system autonomously analyzes CT images, identifies patients at risk of hematoma expansion, and generates predictions, thereby achieving high precision while maintaining ease of operation through automation.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual visual assessment with automated deep learning analysis, substituting human operators with an intelligent system that provides both high precision and operational simplicity. This substitution eliminates the trade-off by achieving superior accuracy through automated feature extraction while reducing operational complexity through workflow automation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS20240354938A1Systems and Methods for Prediction of Hematoma Expansion Using Automated Deep Learning Image Analysis
Publication Date: 2024.10.24 NORTHWESTERN UNIV
  • US20240354938A1 patent drawing
  • US20240354938A1 patent drawing
  • US20240354938A1 patent drawing

AI summary

A computing device for prediction of hematoma expansion using deep learning techniques includes a processor and memory in communication with the processor and storing instructions that, when read by the processor, cause the computing device to: retrieve, from a data store, electronic data corresponding to one or more diagnostic scans of a patient, preprocess the one or more diagnostic scans of the patient, perform deep learning analysis based on deep learning model trained to classify hematoma expansion, predict, based on the deep learning analysis of the one or more diagnostic scans, a probability of hematoma expansion for the patient, and provide, via a display, the probability of hematoma expansion for the patient as a combination of a heat map and a diagnostic scan of the one or more diagnostic scans of the patient.