Deep Learning Tomographic Image Reconstruction

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Solution Overview

Problem

Current medical imaging technologies face limitations in image formation and reconstruction, particularly in handling low-quality data and artifacts, such as metal artifacts, and existing methods are inefficient in improving image quality without significant computational costs.

Innovation Solution

The implementation of deep learning algorithms, specifically deep neural networks, for image reconstruction from raw data in medical imaging modalities like CT, MRI, and X-ray, which can refine initial images obtained through conventional algorithms to produce high-quality reconstructed images, leveraging big data and prior knowledge for improved feature extraction and artifact reduction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional reconstruction algorithms are used on low-quality tomographic data, then image reconstruction can be performed, but the reconstructed images contain significant noise and artifacts

Engineering Contradiction:
Improveimage qualityVSAvoidnoise and artifacts
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The system performs preliminary actions by training the deep neural network in advance with large amounts of labeled tomographic data and corresponding ground truth images. This pre-trained network is then applied to reconstruct images from new low-quality data, eliminating the need for time-consuming iterative optimization during actual reconstruction and significantly reducing noise and artifacts while maintaining high image quality.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If iterative reconstruction methods are used to improve image quality, then image quality improves, but computational time and resources increase significantly

Engineering Contradiction:
Improveimage qualityVSAvoidcomputational time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The invention substitutes the traditional mechanical iterative optimization process with a deep neural network-based system. Instead of performing repeated mathematical iterations to minimize reconstruction error, the pre-trained network directly maps raw tomographic data to high-quality images in a single forward pass, achieving comparable or superior image quality with dramatically reduced computational time.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If deep learning algorithms are applied to image reconstruction, then image quality and diagnostic performance improve, but system complexity increases

Engineering Contradiction:
Improvediagnostic performanceVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system resolves complexity by performing all complex deep learning operations in advance during the training phase. The trained network model is then deployed as a fixed computational pipeline that requires minimal adjustment during actual reconstruction tasks, maintaining high diagnostic performance while simplifying operational complexity.

Inventive Principle:
Principle #10Preliminary action

4Measurement precision

If more data is collected to train deep learning models, then reconstruction accuracy improves, but data storage and processing requirements increase

Engineering Contradiction:
Improvereconstruction accuracyVSAvoiddata volume
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The system optimizes the balance between training data volume and reconstruction accuracy by carefully selecting representative training datasets and adjusting network architecture parameters. The training process transforms large volumes of raw data into compact model parameters, achieving high reconstruction accuracy while the trained model requires minimal storage space for deployment.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS10970887B2Tomographic image reconstruction via machine learning
Publication Date: 2021.04.06 RENESSELAER POLYTECHNIC INST
  • US10970887B2 patent drawing
  • US10970887B2 patent drawing
  • US10970887B2 patent drawing

AI summary

Tomographic/tomosynthetic image reconstruction systems and methods in the framework of machine learning, such as deep learning, are provided. A machine learning algorithm can be used to obtain an improved tomographic image from raw data, processed data, or a preliminarily reconstructed intermediate image for biomedical imaging or any other imaging purpose. In certain cases, a single, conventional, non-deep-learning algorithm can be used on raw imaging data to obtain an initial image, and then a deep learning algorithm can be used on the initial image to obtain a final reconstructed image. All machine learning methods and systems for tomographic image reconstruction are covered, except for use of a single shallow network (three layers or less) for image reconstruction.