Deep TMS Coil Array for Non-Invasive Deep Brain Targeting
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Solution Overview
Problem
Existing transcranial magnetic stimulation technologies are limited to superficial brain regions, failing to effectively reach deep tissues such as the temporal lobe, basal ganglia, and thalamus, and lack non-invasive alternatives to invasive deep brain stimulation (DBS).
Innovation Solution
A device employing a deep stimulation coil module with multiple coil groups generating a superimposed electromagnetic field, adjusted for precise targeting and superposition to reach deep brain regions, incorporating power and temperature detection for safety.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Length of stationary object
If existing magnetic stimulation modules (annular coils, 8-shaped coils, biconical coils, H-shaped coils) are used, then the stimulation depth is limited to 2-6 cm, but the requirement to reach deep brain tissues (temporal lobe, basal ganglia, thalamus) cannot be met
Solution Approach 1:
The patent divides the stimulation system into multiple independent coil groups, each capable of generating magnetic fields that can be independently controlled. This segmentation allows the magnetic fields from multiple coils to be superimposed, extending the effective stimulation depth beyond what single coils can achieve (2-6 cm), enabling reach to deep brain structures like temporal lobe, basal ganglia, and thalamus.
Solution Approach 2:
The patent combines multiple coil groups to generate superimposed magnetic fields. By merging the magnetic field contributions from multiple coils positioned at different orientations, the system achieves enhanced penetration depth and the ability to target deep brain regions that cannot be reached by conventional single-coil approaches.
2Length of stationary object
If invasive deep brain stimulation (DBS) is used to reach deep brain tissues, then deep brain regions can be stimulated, but the procedure is expensive and incapable of adjusting target points once implanted
Solution Approach 1:
The patent replaces the invasive mechanical implantation system (DBS) with a non-invasive electromagnetic field system. By using multiple coil groups that can be externally positioned and controlled, the system achieves deep brain stimulation without surgical implantation, thereby avoiding the inability to adjust target points and the high cost associated with invasive procedures.
Solution Approach 2:
The patent employs coil groups that can be dynamically positioned and oriented in different configurations. This dynamic adjustability allows the system to target different deep brain regions by repositioning the coils, providing flexibility that invasive DBS lacks, while maintaining the non-invasive nature of the treatment.
3Length of stationary object
If multiple coil groups are used to generate superimposed magnetic fields for deep stimulation, then deep brain regions can be reached, but the system complexity increases
Solution Approach 1:
The patent designs coil groups that can serve multiple functions: each coil group can be positioned at different orientations and combined with other coils to target various deep brain regions. This multi-functionality reduces the need for entirely separate systems for different stimulation targets, managing complexity while maintaining versatility in reaching deep brain structures.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Accurately delivers a non-invasive transcranial magnetic field to deep brain regions beyond 6 cm, ensuring safety and efficiency by adjusting coil positions and power usage, and providing precise stimulation.
Implementation Method 1
The deep stimulation coil module is configured to generate a superimposed magnetic field and transmit the superimposed magnetic field to the target region
Data Source
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AI summary
A device for deep transcranial magnetic stimulation regulation treatment is provided. The device includes an upper computer control software, configured to send a stimulation instruction to a system main control module according to predetermined parameter data; a system main control module, configured to send a control enable signal to a stimulation coil excitation power module when receiving the stimulation instruction; a stimulation coil excitation power module, configured to provide a current to a deep stimulation coil module according to the control enable signal; and a deep stimulation coil module, configured to generate a superimposed magnetic field and transmit the superimposed magnetic field to a target region. The deep stimulation coil module includes multiple coil groups. Each coil group includes two coils. There is an overlapping part among magnetic fields of the multiple coil groups, and the overlapping part corresponds to a predetermined target region.