Triple Halo Coil Configuration for Depth-Selective Brain Stimulation
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Solution Overview
Problem
Existing TMS coils are limited to stimulating superficial brain regions, and conventional methods overstimulate the surface of the brain when attempting to stimulate deeper regions, making it challenging to treat neurological disorders effectively.
Innovation Solution
The Triple Halo Coil configuration, comprising three elliptical coils positioned at specific angles relative to a top coil, enhances magnetic field penetration to deep brain regions, reducing surface overstimulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Force
If conventional TMS coils are used to stimulate deep brain regions, then magnetic field strength at depth can be increased, but surface overstimulation occurs
Solution Approach 1:
The patent divides a single large coil into multiple smaller coils arranged in a specific geometric pattern (e.g., hexagonal or circular arrays). This segmentation allows the magnetic fields from individual coils to constructively interfere at deep targets while destructively interfering at the surface, thereby achieving depth-selective stimulation without surface overstimulation
Solution Approach 2:
The patent transitions from conventional single-plane coil configurations to multi-dimensional spatial arrangements of multiple coils. By positioning coils in three-dimensional space with specific orientations and spacing, the system creates focused magnetic field patterns that penetrate deeply while maintaining surface field control through geometric phase cancellation
2Force
If magnetic field strength is increased to reach deep brain regions, then deep brain stimulation effectiveness improves, but the magnetic field decays rapidly with distance making it challenging
Solution Approach 1:
The patent designs coil arrays with universal geometric patterns (such as hexagonal or circular configurations) that can be applied to multiple deep brain targets by simply adjusting the activation sequence and timing parameters. This universal framework allows the same physical coil arrangement to stimulate different deep structures (thalamus, hippocampus, substantia nigra) without requiring custom coil designs for each target
Solution Approach 2:
The patent employs periodic pulsed stimulation patterns with specific duty cycles and inter-pulse intervals. By delivering magnetic pulses in periodic trains rather than continuous waves, the system achieves cumulative deep brain stimulation effects while allowing thermal dissipation and neural recovery, thereby enabling effective deep stimulation without excessive energy input that would increase device complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The Triple Halo Coil significantly increases magnetic field strength in deep brain regions like the thalamus, hypothalamus, and hippocampus, enabling non-invasive treatment of neurological disorders such as Parkinson's disease.
Implementation Method 1
Time varying magnetic fields generate eddy currents in the brain. When a sufficient amount of electric potential is induced on the neurons, it causes depolarization of neuronal membrane and initiates an action potential.
Implementation Method 2
The Triple Halo Coil configuration, comprising three elliptical coils positioned at specific angles relative to a top coil, enhances magnetic field penetration to deep brain regions
Data Source
AI summary
A coil configuration and method for transcranial magnetic stimulation enabling stimulation of deep regions of the brain without excessively stimulating the cortex is provided. The coil configuration utilizes at least one coil to produce an off-plane magnetic field to enhance the magnetic field from a top TMS coil. In one configuration at least a single variable position coil referred to as the Variable Halo Coil and positionable vertically and/or angularly is used.


