Diagnostic Pulse Defibrillation Assessment

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Solution Overview

Problem

Current defibrillator systems lack an effective method to determine the likelihood of defibrillation therapy success, relying on inaccurate statistical correlations and indirect information from VF waveforms, which can lead to inappropriate treatment protocols during cardiac arrest.

Innovation Solution

A system and method that apply diagnostic electrical pulses to assess the patient's physiologic response, allowing for the identification of a recommended treatment protocol based on mechanical and electrical cardiac responses, thereby enhancing the effectiveness of defibrillation therapy by determining the patient's responsiveness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If statistical correlations and indirect VF waveform analysis are used to predict defibrillation responsiveness, then treatment protocols can be recommended, but the predictions are inaccurate and results can be corrupted by artifact

Engineering Contradiction:
Improveprediction accuracyVSAvoidresult reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent introduces an intermediary diagnostic pulse signal between the defibrillation waveform and the heart tissue. This intermediary signal serves as a mediator to directly assess cardiac responsiveness by measuring impedance changes in response to the diagnostic pulse, rather than relying on indirect statistical correlations from VF waveform analysis. The intermediary measurement provides a more accurate and reliable indicator of defibrillation responsiveness.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If diagnostic pulses are applied to assess patient responsiveness, then appropriate resuscitation protocols can be identified, but additional time is required for assessment

Engineering Contradiction:
Improveresponsiveness assessment accuracyVSAvoidassessment time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies partial action by using a low-energy diagnostic pulse that is sufficient to assess cardiac responsiveness but excessive enough to elicit a measurable impedance change. This partial diagnostic signal provides the necessary information to determine defibrillation responsiveness without delivering full defibrillation energy, thereby reducing the time required for accurate assessment while maintaining measurement precision.

Inventive Principle:
Principle #16Partial or excessive action

3Productivity

If immediate defibrillation therapy is administered without assessment, then rapid perfusion restoration may be achieved, but inappropriate treatment may be delivered to patients who would respond better to CPR or drugs

Engineering Contradiction:
Improvetreatment speedVSAvoidtreatment appropriateness
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent implements preliminary action by administering a diagnostic pulse before committing to full defibrillation therapy. This preliminary assessment measures impedance changes in response to the diagnostic signal, providing advance information about cardiac responsiveness. Based on this preliminary data, the system can determine whether immediate defibrillation is appropriate or whether alternative treatments such as CPR or drug administration would be more effective, thereby ensuring treatment appropriateness while maintaining rapid response.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables quick, noninvasive, and simple implementation in existing defibrillation devices, allowing for immediate and appropriate resuscitation protocols, such as CPR or drug administration, to enhance the patient's responsiveness to defibrillation therapy, potentially saving lives by improving treatment efficacy during cardiac arrest.

Implementation Method 1

A defibrillator provides an electrical stimulus to the heart in an attempt to convert the irregular heat beat to a normal sinus rhythm

Methodology Applied
Scientific EffectElectrical stimulation: Electrical Impedance Tomography

Implementation Method 2

The defibrillator measures impedance changes in response to the diagnostic pulse to determine a likelihood that the patient's heart will respond to defibrillation therapy

Methodology Applied
Scientific EffectElectrical impedance measurement: Electrical Impedance Tomography

Data Source

PatentUS8731658B2System and method for using diagnostic pulses in connection with defibrillation therapy
Publication Date: 2014.05.20 PHYSIO CONTROL CORP
  • US8731658B2 patent drawing
  • US8731658B2 patent drawing
  • US8731658B2 patent drawing

AI summary

An external defibrillator system is disclosed that generates and applies a diagnostic signal to the patient in conjunction with defibrillation therapy. The diagnostic signal is designed to elicit a physiologic response from the patient's heart, namely, mechanical cardiac response and electrical cardiac response, electrical cardiac response only, or no cardiac response. Depending upon the type of cardiac response detected, the system selects an appropriate resuscitation protocol that considers the likely responsiveness of the patient to defibrillation therapy. In one practical embodiment, a stimulus signal is applied to patients that show mechanical and electrical capture in response to the diagnostic signal. The stimulus signal maintains the mechanical capture (and, therefore, perfusion) for a period of time prior to the delivery of a defibrillation pulse.