Deformable Clot Retrieval Device With Anchoring Spikes
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Solution Overview
Problem
Current medical devices for removing blood clots from narrow blood vessels often cause damage to the vessels and risk clot fragmentation, limiting their effectiveness and safety in treating strokes.
Innovation Solution
A medical device with a guidewire and capturing unit that deforms to form a cage-like structure, anchoring and capturing blood clots without fracturing them, using flexible and deformable elongated elements with spikes that change orientation to secure the clot, allowing for safe extraction without damaging the vessel.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current medical devices are used to remove blood clots from narrow blood vessels, then clot removal is achieved, but vessel damage and clot fragmentation occur
Solution Approach 1:
The device employs flexible elongated elements that can conform to the vessel wall and clot geometry, allowing gentle engagement without rigid contact that would cause damage. These elements flexibly adapt to narrow blood vessels while maintaining effective clot capture
Solution Approach 2:
The device transitions from a compressed delivery state to an expanded working state, and can dynamically adjust its configuration during retrieval. This dynamic behavior allows the device to navigate narrow vessels in a compact form while expanding to effectively capture and secure clots without excessive force
2Reliability
If current medical devices are used to remove blood clots, then clot removal is achieved, but emboli risk increases due to clot fragmentation
Solution Approach 1:
The device performs preliminary engagement and secure anchoring of the clot before retrieval begins. The elongated elements penetrate and anchor into the clot structure in advance, ensuring firm attachment that prevents fragmentation during the extraction process
Solution Approach 2:
The device divides the clot capture function across multiple elongated elements with spikes, where each element independently engages the clot. This segmented approach distributes the capture forces, reducing stress concentration that would otherwise cause clot fragmentation
3Reliability
If chemical thrombolytics are used for stroke treatment, then clot dissolution is achieved, but treatment time window is limited and intracranial hemorrhage risk increases
Solution Approach 1:
The device replaces chemical thrombolytic therapy with a mechanical clot removal system. Instead of relying on chemical dissolution processes that require extended time windows and carry hemorrhage risks, the device mechanically captures and extracts the clot intact, enabling immediate removal without chemical agents
Solution Approach 2:
The device directly extracts the clot from the vessel through mechanical capture and retrieval. This extraction approach removes the obstruction immediately without requiring the clot to dissolve chemically, thereby eliminating the time window limitations and hemorrhage risks associated with thrombolytic therapy
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively removes blood clots with minimal vessel damage and reduced risk of emboli, extending the treatment window for stroke patients and improving re-canalization rates without the need for chemical thrombolytics.
Implementation Method 1
deforming a corpus-engaging segment of the device causes the formation of a cage-like structure that physically anchors into the clot
Implementation Method 2
the elongated elements arch radially away from the guidewire defining a loop with an apex formed by the apex-forming portion
Implementation Method 3
each spike switches its orientation upon deformation of the elongated element from the non-deformed state to the deformed state
Data Source
Figure 1
Figure 2
Figure 3A
AI summary
The disclosure provides medical devices, systems and methods for retrieval and/or extraction of a corpus located in a tubular organ. Systems of this disclosure are suitable for carrying out various procedures for removal of occlusive corpus from tubular organs, for example thrombectomy.