Deformable Pre-Packaged Injection Device for Liquid Mixing

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Solution Overview

Problem

Existing deformable cartridges for injecting liquid mixtures face challenges in maintaining isolation between containment chambers, leading to potential stability loss of active ingredients and increased complexity and cost in production and use.

Innovation Solution

A deformable pre-packaged injection device with separate containment chambers for liquid and powder components, connected by rigid or semi-rigid mechanical and fluidic means, allowing for inelastic deformation to mix and inject the components without external tools.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If deformable cartridges with separate containment chambers are used to store and mix components, then the stability of active ingredients is improved, but the isolation between chambers becomes difficult to maintain

Engineering Contradiction:
Improvestability of active ingredientsVSAvoidisolation between containment chambers
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The deformable cartridge is nested within a syringe barrel, creating a hierarchical structure where the cartridge contains multiple chambers and the syringe provides an outer protective and functional housing. This nesting arrangement maintains isolation between chambers while enabling the mixing function through coordinated deformation of the cartridge within the syringe structure.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The cartridge is divided into multiple separate containment chambers that are physically isolated from each other during storage. Each chamber can be independently sealed and maintained at different pressures, allowing stable storage of different active ingredients without interaction until the mixing moment.

Inventive Principle:
Principle #1Segmentation

2Ease of operation

If a specific tool is used to deform chambers for mixing and injection, then the mixing function is achieved, but the device complexity and production cost increase

Engineering Contradiction:
Improvemixing and injection functionVSAvoidproduction cost and device structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The syringe integrates multiple functions into a single device: it houses the deformable cartridge, provides the injection needle, enables chamber deformation through plunger action, and facilitates both mixing and injection operations. This merging eliminates the need for separate external tools and reduces overall system complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The syringe serves multiple purposes: storage container, mixing device, injection tool, and actuation mechanism. The plunger both seals the cartridge during storage and deforms the chambers during mixing, while the needle serves both as a seal and an injection pathway. This multi-functionality reduces the number of components needed.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If the operator uses a specific tool to crush chambers, then the mixing process is controlled, but the ease of use and sensitivity are reduced compared to traditional syringes

Engineering Contradiction:
Improvecontrolled mixing processVSAvoidoperator sensitivity and ease of use
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The deformable cartridge structure enables self-mixing through the natural deformation caused by plunger insertion. The chambers are designed to collapse and mix contents automatically when the plunger is inserted, eliminating the need for the operator to manually crush or deform rigid chambers. This maintains operator sensitivity and ease of use similar to traditional syringes.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device allows for efficient reconstitution and injection of liquid mixtures at the point of use, reducing production costs, simplifying operations, and maintaining sensitivity and ease of use comparable to traditional syringes.

Implementation Method 1

at least a first wall deformable by compression; at least a second wall deformable by compression so as to allow the transfer of the second component from the second containment chamber P21 to the first containment chamber P11

Methodology Applied
Scientific EffectInelastic deformation: Deformation

Data Source

PatentEP4213918B1Deformable pre-packaged device for injecting a liquid
Publication Date: 2025.04.09 OROFINO PHARMACEUTICALS GROUP SRL
  • EP4213918B1 patent drawingFigure 1(a)~1(b)
  • EP4213918B1 patent drawingFigure 2
  • EP4213918B1 patent drawingFigure 3(a)~3(d)

AI summary

Deformable pre-packaged device for injecting a liquid The present invention relates to a device (100) for injecting a reconstitutable liquid mixture, comprising a first (40) and a second (30) containment chamber of a first and a second component of the liquid mixture, respectively; first mechanical and fluidic connection means (43,33) between said first (40) and said second (30) containment chambers, as well as second mechanical and fluidic connection means (20) between said second containment chamber (30) and an injection needle (10); wherein: - the first chamber (40) comprises a first upper (41) and lower (42) surface in the shape of a (truncated) cone having the same axis of symmetry (S) and a common base circumference (44), - the first upper (41) and lower (42) surfaces have a common base (44) and opposite extensions forming a non-zero angle β therebetween; - the second containment chamber (30) comprises a second upper (31) and lower (32) surface in the shape of a (truncated) cone, both having said axis of symmetry (S) and a common base circumference (34), - the second upper (31) and lower (32) surfaces have a common base (34) and opposite extensions forming a non-zero angle a therebetween; - the first (42) and the second (32) lower surfaces are deformable by compression.