Degassed Arterial Infusion System with Capped Lines

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Solution Overview

Problem

Arterial infusions during medical procedures, such as angiography, often result in arterial gas embolism due to air bubbles in the infused liquid, which can lead to serious complications like stroke and heart attack, and current methods for removing bubbles are time-consuming and costly.

Innovation Solution

A sterile degassed fluid delivery system pre-filled with degassed medicament and multiple capped lines that allow for immediate, bubble-free medicament infusion, reducing the need for assembly and monitoring, and incorporating features like a capping manifold and drip chambers for efficient flushing and air scavenging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional IV bags and tubes are used with manual bubble removal techniques, then the system is simpler and easier to assemble, but air bubbles remain in the infused liquid causing arterial gas embolism risk

Engineering Contradiction:
Improvebubble-free infusionVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs degassing of the saline solution before the medical procedure begins. Thedegassing chamber removes dissolved gases from the saline during storage, so that when the saline isinfused through the catheter, no air bubbles are present to cause embolism. This preliminary actioneliminates the need for manual bubble removal during the procedure.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces a degassing chamber as an intermediary component between the salinebag and the infusion catheter. This chamber acts as a mediator that captures and removes airbubbles from the saline flow before the saline enters the arterial system, preventing embolismwithout requiring complex modifications to the entire infusion system.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If manual bubble removal techniques are used during the procedure, then the equipment is simpler, but significant procedural time is wasted on bubble removal and monitoring

Engineering Contradiction:
Improveprocedural efficiencyVSAvoidtime for bubble removal
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The system performs degassing of the saline solution before the medical procedure begins. Thedegassing chamber removes dissolved gases from the saline during storage, so that when the saline isinfused through the catheter, no air bubbles are present to cause embolism. This preliminary actioneliminates the need for manual bubble removal during the procedure.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The degassing chamber is designed to automatically remove air bubbles from the saline solutionwithout requiring manual intervention. The chamber uses pressure differential and/or centrifugal forcest to separate and collect air bubbles, allowing the system to self-maintain a bubble-free state duringinfusion, freeing medical staff to focus on patient care.

Inventive Principle:
Principle #25Self-service

3Object-affected harmful factors

If traditional IV systems are used requiring continuous monitoring for bubbles, then the system is simpler, but medical personnel must be diverted from patient care to monitor for bubbles

Engineering Contradiction:
Improvearterial gas embolism riskVSAvoidmonitoring requirement
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The patent extracts the harmful air bubbles from the saline solution using a dedicated degassing chamber. The chamber is designed to capture and collect air bubbles as the saline flows through it, separating the gas phase from the liquid phase. This extraction process eliminates the source of arterial gas embolism risk before the saline enters the patient's arterial system.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a degassing chamber as an intermediary component between the salinebag and the infusion catheter. This chamber acts as a mediator that captures and removes airbubbles from the saline flow before the saline enters the arterial system, preventing embolismwithout requiring complex modifications to the entire infusion system.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of manufacture

If manual bubble removal and monitoring is performed, then the system is simpler, but significant costs are incurred including operating room time and human resources

Engineering Contradiction:
Improvesystem simplicityVSAvoidprocedural cost
Core Design Contradiction:
Ease of manufactureVSLoss of energy

Solution Approach 1:

The system performs degassing of the saline solution before the medical procedure begins. Thedegassing chamber removes dissolved gases from the saline during storage, so that when the saline isinfused through the catheter, no air bubbles are present to cause embolism. This preliminary actioneliminates the need for manual bubble removal during the procedure.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The degassing chamber is designed to automatically remove air bubbles from the saline solutionwithout requiring manual intervention. The chamber uses pressure differential and/or centrifugal forcest to separate and collect air bubbles, allowing the system to self-maintain a bubble-free state duringinfusion, freeing medical staff to focus on patient care.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system significantly reduces the risks and costs associated with arterial infusion by ensuring a bubble-free infusion solution, minimizing procedural delays, and providing immediate availability of infusion liquids, thus enhancing safety and efficiency during medical procedures.

Implementation Method 1

The system volume is filled with a degassed saline solution to the exclusion of bubble-forming gas

Methodology Applied
Scientific EffectDegassing:

Data Source

PatentUS20240165321A1Degassed Infusion System for Arterial Infusion
Publication Date: 2024.05.23 ALJUBOORI ZAID
  • US20240165321A1 patent drawing
  • US20240165321A1 patent drawing
  • US20240165321A1 patent drawing

AI summary

A system for arterial infusion provides integrally attached IV bag and multiple IV delivery lines pre-charged with degassed saline solution and sealed by capping the distal ends of the IV lines. Bubble-free arterial infusion may thus be quickly obtained by selecting an individual line, removing its cap, and connecting it to an appropriate needle or catheter.