Controlled Release Dental Anesthetic Socket Packing

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Solution Overview

Problem

Current methods for managing post-operative dental pain rely heavily on narcotics and self-administration of local anesthetics, which pose risks of overdose and adverse effects, and existing sustained release formulations do not effectively coordinate with pre-surgical doses to prevent these issues.

Innovation Solution

A solid controlled release pharmaceutical formulation of local anesthetics is placed in the dental socket after tooth extraction, designed to release anesthetic in coordination with pre-administered local anesthetics, providing sustained pain relief for 4 to 5 days without the need for narcotics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If narcotics are used to manage post-operative dental pain, then pain relief is effective, but serious side effects occur including addiction, respiratory depression, and cardiac arrest

Engineering Contradiction:
Improvepain relief effectivenessVSAvoidside effects including addiction and respiratory depression
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The invention extracts the harmful element (narcotics) from the pain management system by replacing it with a local anesthetic delivery system. The controlled release formulation delivers anesthetic directly to the surgical site, eliminating the need for systemic narcotic administration while maintaining effective pain relief.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention introduces a controlled release formulation as an intermediary between the local anesthetic and the patient's pain receptors. This intermediary system provides sustained delivery of the anesthetic agent directly at the surgical site, avoiding the need for narcotic intermediaries that cause harmful side effects.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Duration of action of moving object

If additional local anesthetics are administered post-surgery, then pain relief is extended, but the risk of overdose increases due to additive effects with pre-surgical doses

Engineering Contradiction:
Improveduration of pain reliefVSAvoidoverdose risk from additive effects
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The invention applies preliminary action by administering the controlled release formulation immediately during surgery, coordinated with the pre-surgical local anesthetic dose. The formulation is designed to begin releasing anesthetic as the initial dose wears off, preventing gaps in pain relief while avoiding dangerous accumulation through controlled release kinetics.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The controlled release formulation provides periodic action by delivering the anesthetic in a controlled, time-dependent manner. The release profile is designed to match the declining levels of pre-surgical anesthetic, creating a coordinated periodic delivery pattern that extends duration while maintaining safe concentrations.

Inventive Principle:
Principle #19Periodic action

3Productivity

If long duration local anesthetics are used to reduce administration frequency, then the number of doses is reduced, but rapid onset creates substantial risk of overdose when combined with pre-surgical doses

Engineering Contradiction:
Improvereduction in administration frequencyVSAvoidoverdose risk from rapid onset
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The invention applies dynamics by using a controlled release formulation that adjusts the release rate of the anesthetic over time. The formulation provides sustained delivery without rapid onset, creating a dynamic release profile that extends duration while maintaining safe concentrations throughout the delivery period.

Inventive Principle:
Principle #15Dynamics

4Ease of operation

If patient self-administration of local anesthetics is allowed, then convenience is improved, but safety deteriorates due to inability to time administration properly and risk of overdose

Engineering Contradiction:
Improvepatient convenienceVSAvoidsafety from overdose
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The controlled release formulation provides self-service functionality by automatically delivering the anesthetic at the appropriate time and rate without patient intervention. The formulation eliminates the need for patient timing decisions while maintaining convenient availability, as the drug delivers itself in a controlled manner over the desired period.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces the risk of overdose and adverse effects by coordinating the release of the second anesthetic with the decline of the first, providing prolonged pain relief without the use of narcotics, thus enhancing patient safety and comfort post-surgically.

Implementation Method 1

The present invention provides a biodegradable polymer matrix formulation of a local anesthetic

Methodology Applied
Scientific EffectBiodegradation: Decomposition (biological)

Implementation Method 2

controlled release pharmaceutical formulation...designed to release anesthetic in coordination with pre-administered local anesthetics

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentUS8523569B2Controlled release local anesthetic for post dental surgery and method of use
Publication Date: 2013.09.03 RILENTO PHARMA LLC

AI summary

The present invention relates to a method of delivering local anesthetic after dental extraction surgery. The present invention relates to packing the tooth socket with a tinned release local anesthetic which is coordinated with an initial local anesthetic and which lasts up to 5 days. The socket can be surgically sealed or the implant can act as the sealing means.