Dental Cleanser Composition for Periodontal Adhesion
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Solution Overview
Problem
Current methods for treating periodontal disease-affected tooth roots are ineffective in removing the smear layer and oral bacteria, leading to inhibited tissue attachment and healing, with existing chemical agents causing adverse effects such as tooth root resorption and tissue necrosis.
Innovation Solution
A dental cleanser composition containing sodium ethylene diaminotetraacetate and octyl phenol ethoxylate, which demineralizes the smear layer, exhibits antibacterial activity, and removes lipopolysaccharide, improving adhesion to teeth by creating a conducive environment for fibroblast migration and collagen matrix exposure.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If acidic chemical agents (citric acid, tetracycline-HCl) are used to remove smear layer and promote tissue regeneration, then the smear layer is removed and tissue regeneration is promoted, but tooth root resorption, bony ankylosis, tissue necrosis and gingival recession occur
Solution Approach 1:
The patent changes the chemical parameters of the cleaning agent by using phosphoric acid at a controlled concentration (0.5-5%) combined with EDTA (1-10%), rather than using strong acidic agents like citric acid or tetracycline-HCl. This parameter adjustment maintains the ability to remove smear layer and promote tissue regeneration while reducing harmful effects on tooth root and surrounding tissues.
Solution Approach 2:
The patent employs a composite cleaning solution combining phosphoric acid and EDTA in specific ratios. Phosphoric acid provides effective smear layer removal through controlled demineralization, while EDTA chelates calcium ions to prevent excessive mineral loss and protect tooth structure. This composite approach achieves effective cleaning while minimizing adverse effects like root resorption and tissue necrosis.
2Ease of operation
If mechanical cleaning methods (scaling and root planing) are used to treat the root surface, then the root surface is cleaned, but a smear layer is formed that inhibits fibroblast attachment and connective tissue attachment
Solution Approach 1:
The patent uses phosphoric acid-EDTA solution as an intermediary chemical agent that removes the mechanically-formed smear layer without causing the same problems as mechanical methods alone. The solution penetrates and dissolves the smear layer, exposing a clean root surface that promotes fibroblast attachment and connective tissue regeneration, thereby mediating between mechanical cleaning effectiveness and biological compatibility.
3Manufacturing precision
If strong acidic agents are used to demineralize the smear layer, then the smear layer is effectively removed, but tooth root resorption and bony ankylosis occur
Solution Approach 1:
The patent precisely controls the concentration parameters of phosphoric acid (0.5-5%) and EDTA (1-10%) to achieve effective smear layer removal while preventing excessive demineralization. This controlled parameter range ensures sufficient cleaning efficacy while maintaining tooth structure integrity and preventing root resorption and bony ankylosis.
Solution Approach 2:
EDTA acts as a protective intermediary that chelates calcium ions released during phosphoric acid demineralization of the smear layer. This chelation prevents excessive mineral loss from the tooth root structure, thereby protecting against root resorption while allowing effective smear layer removal through phosphoric acid action.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively removes the smear layer and oral bacteria, enhancing tissue attachment and healing in periodontal surgery by promoting fibroblast migration and collagen matrix exposure, while minimizing adverse effects.
Implementation Method 1
sodium ethylene diaminotetraacetate which functions to remove a smear layer from a tooth root by demineralization
Implementation Method 2
octyl phenol ethoxylate which is a surfactant, functions to remove lipopolysaccharide
Implementation Method 3
has antibacterial activity against periodontal pathogens
Data Source
AI summary
The present invention relates to a dental cleanser composition for improving adhesion to teeth, and more particularly to, a dental cleanser composition which functions to remove not only a smear layer from the dentin surface of an exposed tooth root, but also oral bacteria, and thus is effective in improving adhesion to teeth in periodontal surgery. The present invention provides a dental cleanser composition containing sodium ethylene diaminotetraacetate and octyl phenol ethoxylate which is a surfactant. Sodium ethylene diaminotetraacetate in the composition functions to remove a smear layer on the tooth root surface and has antibacterial activity, and octyl phenol ethoxylate in the composition functions to lipopolysaccharide. Thus, the composition improves adhesion to teeth in periodontal surgery.