Self-Adhesive Dental Composition via Hydrolysis-Stable Amide Bonding
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current dental compositions require primers for adhesion to hard dental tissues, are not hydrolysis-stable, and lack sufficient adhesion to both enamel and dentin, leading to potential degradation and bacterial invasion.
Innovation Solution
A dental composition comprising a particulate filler and a hydrolysis-stable polymerizable compound with a linker group containing nitrogen atoms and acidic groups, which forms an amide bond with a polymerizable moiety, allowing for self-adhesive properties without a primer and maintaining stability in acidic environments.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a primer is used to improve adhesion to hard dental tissue, then adhesion is improved, but the complexity of the dental procedure increases
Solution Approach 1:
The patent combines the primer and restorative material into a single integrated composition. The restorative material itself contains acidic functional groups and coupling agents that provide both etching/primer functions and structural restoration functions, eliminating the need for separate primer application steps while maintaining reliable adhesion to hard dental tissue.
Solution Approach 2:
The restorative material is designed to perform multiple functions simultaneously: it provides structural restoration, contains acidic groups for etching the tooth surface, includes coupling agents for chemical bonding, and offers hydrolysis stability. This multi-functional design eliminates the need for separate primer and etchant steps.
2Reliability
If a primer is used to demineralize the tooth surface for better adhesion, then adhesion is improved, but the number of treatment steps increases
Solution Approach 1:
The patent merges the demineralization function traditionally performed by separate primer/etchant steps into the restorative material itself. The acidic functional groups within the restorative material perform the demineralization and etching functions while the material is being applied, reducing the overall treatment time and number of steps.
Solution Approach 2:
The restorative material is pre-formulated with acidic groups and coupling agents that are ready to act immediately upon application. This preliminary preparation of adhesion-promoting components within the restorative material eliminates the need for separate preliminary etching and priming steps.
3Reliability
If acidic groups are added to improve adhesion to hard dental tissue, then adhesion is improved, but hydrolysis stability decreases
Solution Approach 1:
The patent uses a composite material system where acidic functional groups are incorporated within a hydrolysis-stable polymer matrix. The composite structure allows the acidic groups to provide adhesion to hard dental tissue while the stable polymer backbone maintains hydrolysis resistance, resolving the contradiction between adhesion and stability.
Solution Approach 2:
The patent modifies the chemical parameters of the restorative material by selecting specific acidic functional groups and polymer backbones that have both adhesion-promoting and hydrolysis-stable characteristics. This parameter optimization allows simultaneous achievement of good adhesion and high hydrolysis stability.
4Device complexity
If a single acidic monomer is used for self-adhesive properties, then the composition is simplified, but sufficient adherability to both enamel and dentin cannot be attained
Solution Approach 1:
The patent employs a composite material approach where multiple functional components are integrated into a single restorative composition. This includes combining different types of acidic functional groups, coupling agents, and polymer matrices to achieve both enamel and dentin adhesion while maintaining composition simplicity and avoiding the need for separate primers.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition provides excellent storage stability and long-term mechanical resistance, enabling direct application on dental surfaces as a one-pack solution, enhancing adhesion to both enamel and dentin while preventing degradation.
Implementation Method 1
a hydrolysis-stable polymerizable compound with a linker group containing nitrogen atoms and acidic groups, which forms an amide bond with a polymerizable moiety
Implementation Method 2
adhesion of the dental composition to both of them is clinically required... the dental composition desireably has a high hydrolysis stability in order to avoid degradation of the composition during storage or when applied to hard dental tissue
Implementation Method 3
a polymerizable hydrolysis-stable compound... moieties containing a polymerizable double bond... when the dental composition is cured by chemical polymerization or photopolymerization
Data Source
AI summary
Dental composition comprising (i) a particulate filler; (ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—Z, wherein Z is COOM, OPO3M2, PO3M2, SO3M, and M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond, a C1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system.