Dental Image Synthesis Using GANs with Semantic Activation Blocks

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Solution Overview

Problem

Current dental image analysis technologies face challenges in automating the diagnosis and treatment planning process due to issues with image quality, orientation, and contamination, as well as the need for accurate identification of anatomical features and periodontal conditions, which can be obscured by overlapping anatomy or improper patient setup.

Innovation Solution

The development of a system that utilizes machine learning models, specifically convolutional neural networks (CNNs), to preprocess dental images by correcting orientation, removing contamination, and labeling anatomical features, enabling accurate identification of periodontal conditions and treatment planning through image domain transfer and adversarial defense mechanisms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual dental image analysis is used, then diagnostic accuracy can be maintained through expert visual inspection, but the process is time-consuming and labor-intensive

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces manual visual inspection (mechanical human analysis) with an automated deep learning system consisting of CNNs and GANs. The system automatically performs image preprocessing, feature extraction, and diagnostic analysis, eliminating the need for time-consuming manual examination while maintaining or improving diagnostic accuracy through algorithmic pattern recognition.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system enables self-service automation where the dental image analysis is performed autonomously by the deep learning models without requiring continuous human intervention. The automated pipeline processes images through multiple stages (preprocessing, segmentation, classification) independently, freeing clinicians from routine analysis tasks.

Inventive Principle:
Principle #25Self-service

2Productivity

If automated image analysis systems are implemented, then processing speed and productivity are improved, but accuracy in identifying anatomical features and periodontal conditions deteriorates due to image quality issues and overlapping anatomy

Engineering Contradiction:
Improveprocessing speedVSAvoidfeature identification accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system performs preliminary actions by implementing a comprehensive image preprocessing stage before main analysis. This includes orientation correction, contamination removal, and quality enhancement that prepare images for accurate feature identification. The preprocessing step addresses image quality issues beforehand, ensuring subsequent analysis operates on optimized input data.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces intermediate processing stages with multiple specialized CNNs that act as mediators between raw images and final diagnosis. The system uses intermediate representations (feature maps, segmented regions) to progressively extract and refine anatomical information, handling overlapping anatomy through multi-stage feature separation and hierarchical processing.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If deep learning models are trained on diverse dental images, then adaptability to different imaging conditions and institutions is improved, but model reliability deteriorates due to adversarial attacks and data contamination

Engineering Contradiction:
Improvecross-institutional adaptabilityVSAvoidmodel robustness
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The system applies preliminary anti-action by implementing adversarial defense mechanisms and data validation protocols before training. The approach includes detecting and removing contaminated samples, applying adversarial training to harden models against attacks, and implementing anomaly detection to prevent adversarial examples from compromising model reliability during the training process.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The patent incorporates feedback loops that monitor model performance and detect adversarial patterns. The system uses validation datasets to provide feedback on model vulnerabilities, continuously refining the adversarial defense strategies and adjusting training parameters to maintain reliability while preserving adaptability across different dental institutions and imaging conditions.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS11367188B2Dental image synthesis using generative adversarial networks with semantic activation blocks
Publication Date: 2022.06.21 RETRACE LABS
  • US11367188B2 patent drawing
  • US11367188B2 patent drawing
  • US11367188B2 patent drawing

AI summary

A GAN is trained to process input images and produce a synthetic dental image. The GAN further takes masks as inputs with each image, the masks labeling pixels of the image corresponding to dental features (anatomy and/or treatments). The GAN includes an encoder-decoder with normalization between stages of the decoder according to the masks. A synthetic image and an unpaired dental image is evaluated by a first discriminator of the GAN to obtain a realism estimate. The synthetic image and an unpaired dental image may be processed using a pretrained dental encoder to obtain a perceptual loss. The GAN is trained with the realism estimate and perceptual loss. Utilization may include modifying a mask for an input image to include or exclude a shape of a feature such that the synthetic image includes or excludes a dental feature.