Medical Image Feature Matching Without Voxel-to-Voxel Registration

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Solution Overview

Problem

Existing image registration and landmark detection techniques for medical imaging are computationally demanding and limited in accuracy and flexibility, particularly when images are captured with different modalities or protocols, making it difficult to accurately locate a given feature across multiple medical images.

Innovation Solution

A method that determines the location of a given feature in medical imaging data by calculating similarity metrics between predefined descriptors for known and candidate locations, allowing for efficient and flexible alignment without relying on voxel-to-voxel mapping or trained classifiers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If voxel-to-voxel mapping is used for image registration, then location accuracy can be improved, but computational demand increases significantly

Engineering Contradiction:
Improvelocation accuracyVSAvoidcomputational efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent divides the image registration task into two stages: first extracting and matching distinctive features (such as corners or edges) between images, then using these matched features to compute the transformation. This segmentation avoids the computationally intensive voxel-to-voxel mapping while maintaining location accuracy through feature-based alignment.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent extracts only the most informative and distinctive regions from the images (such as corners, edges, or textured areas) and uses these extracted features for registration. By taking out only the essential features rather than processing the entire image volume, the method reduces computational burden while preserving registration accuracy.

Inventive Principle:
Principle #2Taking out (Extraction)

2Measurement precision

If landmark detection with trained classifiers is used, then feature location can be determined, but training time and computational resources are consumed

Engineering Contradiction:
Improvefeature location accuracyVSAvoidtraining time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent employs preliminary actions by pre-defining patterns of image elements (such as fixed geometric arrangements or characteristic texture patterns) that can be directly matched between images without requiring time-consuming training. These pre-established patterns serve as universal reference markers that enable rapid registration across different imaging modalities.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Instead of training classifiers to recognize landmarks, the patent creates synthetic copies of distinctive patterns and uses these copies as reference templates for matching. The method copies characteristic image structures into a standardized format that can be efficiently matched across different images, eliminating the need for complex trained classifiers.

Inventive Principle:
Principle #26Copying

3Adaptability or versatility

If image registration is performed across different imaging modalities, then versatility improves, but registration accuracy decreases

Engineering Contradiction:
Improvecross-modality capabilityVSAvoidregistration accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent develops a universal registration approach that works across different imaging modalities (CT, MRI, PET, etc.) by relying on generic distinctive features and pre-defined patterns rather than modality-specific algorithms. The method uses universal geometric relationships and intensity patterns that persist across modalities, enabling accurate registration despite differences in imaging physics and parameters.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12505535B2Determining a location at which a given feature is represented in medical imaging data
Publication Date: 2025.12.23 SIEMENS HEALTHINEERS AG
  • US12505535B2 patent drawing
  • US12505535B2 patent drawing
  • US12505535B2 patent drawing

AI summary

A computer implemented method and apparatus for determining a location at which a given feature is represented in medical imaging data is disclosed. A first descriptor for a first location in first medical imaging data is obtained. The first location is the location within the first medical imaging data at which the given feature is represented. A second descriptor for each of a plurality of candidate second locations in second medical imaging data is obtained. A similarity metric indicating a degree of similarity with the first descriptor is calculated for each of the plurality of candidate second locations. A candidate second location is selected from among the plurality of candidate second locations based on the calculated similarity metrics. The location at which the given feature is represented in the second medical imaging data is determined based on the selected candidate second location.