Desensitizing Toothpaste Using DP-Bioglass for Tubule Occlusion
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Solution Overview
Problem
Conventional desensitizing toothpastes fail to provide lasting relief for dentin hypersensitivity due to ineffective occlusion of dentinal tubules, with existing methods either offering short-term relief or not addressing the root cause of nerve activation.
Innovation Solution
A desensitizing toothpaste containing DP-bioglass, which dissolves to release calcium and phosphate ions, precipitating hydroxyapatite to occlude dentinal tubules and provide long-term sensitivity relief, combined with conventional abrasives and humectants for enhanced efficacy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional desensitizing toothpaste is used, then temporary pain relief is achieved through nerve conduction block, but the dentinal tubules are not effectively occluded and hypersensitivity returns
Solution Approach 1:
The patent changes the chemical composition parameters of the toothpaste by incorporating specific concentrations of calcium phosphate particles (5-20% by weight), fluoride (1000-1500 ppm), and other ingredients to optimize both the occlusion effectiveness and lasting relief of dentin hypersensitivity
Solution Approach 2:
The patent uses a composite formulation combining calcium phosphate particles, fluoride compounds, potassium nitrate, and other ingredients to achieve multiple functions: occluding dentinal tubules, remineralizing enamel, and providing long-term sensitivity relief
2Duration of action of moving object
If protein precipitation method is used to reduce dentinal fluid flow, then temporary reduction in nerve activation occurs, but the cure does not last long
Solution Approach 1:
The toothpaste performs preliminary occlusion of dentinal tubules before nerve activation can occur, using calcium phosphate particles to physically block the tubules and prevent dentinal fluid flow, thereby providing long-term prevention rather than temporary relief
3Manufacturing precision
If simple toothpaste formulations are used, then ease of use and cost-effectiveness are improved, but effective deposition in dentinal tubules and occlusion is not achieved
Solution Approach 1:
The patent optimizes specific formulation parameters including calcium phosphate particle size (1-10 micrometers), fluoride concentration (1000-1500 ppm), and relative ingredient proportions to achieve effective tubule occlusion while maintaining a practical toothpaste formulation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The toothpaste effectively occludes dentinal tubules, providing lasting alleviation of dentin hypersensitivity while also offering temporary relief through potassium nitrate, enhancing cleaning and remineralization with fluoride.
Implementation Method 1
DP-bioglass, which dissolves to release calcium and phosphate ions
Implementation Method 2
precipitating hydroxyapatite to occlude dentinal tubules
Implementation Method 3
enhancing cleaning and remineralization with fluoride
Data Source
AI summary
The present invention discloses a desensitizing toothpaste. Based on the total weight of the desensitizing toothpaste, the desensitizing toothpaste includes: from 5% to 40% by weight of DP-bioglass; from 1% to 5% by weight of thickening agents; from 25% to 35% by weight of humectant; and from 1% to 5% by weight of surfactant, wherein the DP-bioglass includes: 8.4% of Na2O, 40.6% of CaO, 39% of SiO2, and 12% of P2O5 based on the total weight of the DP-bioglass. With the implementation of the present invention, the indication of dentin hypersensitivity can be greatly relieved.