Detecting Apparatus With Pierced Buffer Chamber For Rapid Diagnosis

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Solution Overview

Problem

Existing rapid diagnosis apparatuses for detecting analytes in samples, such as urine and saliva, require complex handling of buffer solutions to maintain pH stability, which can lead to bacterial growth and inaccurate results due to exposure to air.

Innovation Solution

A detecting apparatus with a storage chamber containing a buffer solution and a sharp-pointed portion that releases the solution into a collecting chamber, where it can be used for sample detection, along with a sample collector that prevents leakage and enhances sample extraction efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the buffer solution is stored separately from the detecting apparatus to avoid bacterial growth, then the reliability of detection is improved, but the device complexity and ease of operation deteriorate due to additional steps required to add buffer solution during detection

Engineering Contradiction:
Improvedetection accuracyVSAvoidoperation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The detecting apparatus is divided into functionally independent modules: a buffer solution storage chamber that can be separately replaced, and a sample collection chamber. This segmentation allows the buffer solution to be pre-stored in a sealed environment (maintaining reliability) while being easily accessed during detection without complex operations (reducing operation complexity).

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The buffer solution is prepared and stored in advance in the storage chamber before the actual detection process. This preliminary action eliminates the need for on-site buffer solution preparation or complex handling during detection, simplifying the overall operation while maintaining detection accuracy through pre-equilibrated buffer conditions.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If the buffer solution is exposed to air at room temperature for a long time to maintain availability, then the ease of operation is improved, but the reliability deteriorates due to bacterial growth and pH change

Engineering Contradiction:
Improvebuffer solution availabilityVSAvoidpH stability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The storage chamber is designed with sealed flexible membranes or thin film structures that enclose the buffer solution. These flexible sealing structures maintain the buffer solution in a closed, sterile environment (preventing bacterial growth and pH change) while allowing easy access and exchange of the buffer solution when needed, thus simultaneously achieving reliability and ease of operation.

Inventive Principle:
Principle #30Flexible shells and thin films

3Ease of operation

If the storage chamber is designed to be easily replaceable to simplify operation, then the ease of operation is improved, but the manufacturing precision and structural integrity may deteriorate

Engineering Contradiction:
Improvestorage chamber replaceabilityVSAvoidconnection precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The storage chamber is designed with dynamic connection features that allow it to be easily attached and detached during operation. This dynamic design incorporates standardized connection interfaces and flexible sealing mechanisms that ensure reliable connection (maintaining manufacturing precision) while enabling simple user replacement (improving ease of operation).

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus simplifies the detection process by ensuring the buffer solution is always available and used correctly, improving accuracy and ease of use while preventing bacterial contamination and leakage.

Implementation Method 1

the storage chamber will be pierced by the sharp-pointed portion during the moving process, such that the treating fluid in the storage chamber is released

Methodology Applied
Scientific EffectMechanical Force: Mechanical Force

Implementation Method 2

the carrier has a specific matching form with the collecting chamber; the carrier may be inserted into the collecting chamber

Methodology Applied
Scientific EffectCapillary Action: Capillary Action

Data Source

PatentUS20240261776A1Detecting apparatus
Publication Date: 2024.08.08 ZHEJIANG ORIENT GENE BIOTECH CO LTD
  • US20240261776A1 patent drawing
  • US20240261776A1 patent drawing
  • US20240261776A1 patent drawing

AI summary

The present invention provides a detecting apparatus, including a storage chamber containing a treating fluid; wherein, the detecting apparatus is internally provided with a sharp-pointed portion; the storage chamber may make a movement relative to the sharp-pointed portion; the storage chamber will be pierced by the sharp-pointed portion during the moving process, such that the treating fluid in the storage chamber is released. The detecting apparatus further includes a collecting chamber; the released treating fluid may flow into the collecting chamber; the collecting chamber is disposed inside a first shell and used to contain a sample; an opening is disposed at an upper position of the first shell; the collecting chamber is internally provided with a testing element for detecting an analyte; the testing element is disposed on a carrier, and the carrier has a specific matching form with the collecting chamber. A buffer solution is disposed in an independent chamber of the detecting apparatus, and may be obtained at any time in need of detection and thus, is easy to be used. The carrier has a specific matching form with the collecting chamber in the first shell, such that the carrier has a definite and unique directional position after being inserted into the collecting chamber.