Detection Chip Temperature Control via Integrated Electrodes
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Traditional PCR technologies require large external equipment for temperature control, leading to complex operations, high costs, and low detection efficiency, with temperature changes affecting non-target components and increasing the risk of damage during heating and cooling processes.
Innovation Solution
A reaction device for a detection chip that includes a chip carrier and an electrical signal control unit to apply electrical signals for precise temperature control, combined with a cooling unit and optical detection capabilities, enabling efficient and accurate temperature cycling for digital PCR with reduced equipment volume and simplified operation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Temperature
If traditional external temperature control equipment is used, then temperature control function is achieved, but device complexity and volume increase
Solution Approach 1:
The patent integrates the temperature control function directly into the detection chip by incorporating heating and cooling electrodes within the chip structure itself, merging the temperature control system with the detection platform to eliminate the need for separate external temperature control equipment
Solution Approach 2:
The heating and cooling electrodes are nested within the detection chip structure, with the temperature control components embedded inside the chip rather than placed externally, allowing the chip to contain its own temperature control system
2Temperature
If traditional external temperature control equipment is used, then temperature cycling is achieved, but operation time increases
Solution Approach 1:
The integration of temperature control electrodes directly into the detection chip enables faster thermal response and more efficient temperature cycling, reducing the total operation time compared to external temperature control systems
Solution Approach 2:
The patent replaces mechanical external temperature control systems with an electrical heating and cooling system integrated into the chip, enabling faster and more precise temperature cycling through direct electrical heating and Peltier effect-based cooling
3Temperature
If external temperature control equipment is used, then heating and cooling functions are achieved, but risk of damage to non-target components increases
Solution Approach 1:
The patent extracts the temperature control function from external equipment and relocates it directly into the detection chip, isolating the heating and cooling actions to only the specific reaction areas within the chip and preventing thermal effects from affecting non-target components
Solution Approach 2:
The integrated electrodes enable localized temperature control at specific positions within the detection chip, allowing different regions to be heated or cooled independently according to the specific reaction requirements, thereby avoiding unnecessary thermal exposure to other components
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution achieves high-efficiency, accurate temperature control, direct insertion, and fast digital PCR detection, reducing operation time and minimizing risk to non-target components, while enhancing integration and portability.
Implementation Method 1
an electrical signal control unit, configured to apply an electrical signal to the detection chip so as to drive a heating electrode of the detection chip
Implementation Method 2
a cooling unit, and the cooling unit is configured to cool down the detection chip
Data Source
AI summary
A reaction device for a detection chip and a reaction system are provided. The reaction device includes a chip carrier and an electrical signal control unit. The chip carrier is configured to place and fix the detection chip; and the electrical signal control unit is configured to apply an electrical signal to the detection chip so as to drive a heating electrode of the detection chip.