In-vitro Diagnostic Analyzer Installation Structure

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Solution Overview

Problem

Reagent cards in medical diagnostics face issues with sample solution leakage and extraction due to improper insertion or ambient temperature and pressure conditions, leading to unreliable calibration and detection processes.

Innovation Solution

An installation structure with a hollow needle and air inlet channel for on-off control of the sample solution, allowing gas to enter or exit the sample tube through an air inlet hole, ensuring reliable sealing and preventing leakage or extraction failure, without relying on extrusion or self-reset of the sample inlet channel.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the sample inlet channel is closed by extrusion, then the sample solution can be controlled to flow, but the sample solution may leak when the reagent card is not inserted in place or the pressing part is deviated

Engineering Contradiction:
Improvesample solution control reliabilityVSAvoidsample solution leakage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent introduces a valve core as an intermediary component between the pressing part and the sample inlet channel. The valve core includes a valve body with a valve hole and a valve seat with a sealing hole. The pressing part acts on the valve core to control the valve hole's opening and closing state, which in turn controls the sample solution flow. This intermediary structure ensures reliable sealing and prevents leakage even when the reagent card is not inserted in place or the pressing part is deviated.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If the sample inlet channel is closed by extrusion, then the sample solution can be controlled to flow, but the sample solution cannot be extracted when the ambient temperature is too low or the negative pressure is too large

Engineering Contradiction:
Improvesample solution control reliabilityVSAvoidsample solution extraction failure
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The valve core serves as an intermediary that decouples the sealing function from the extrusion mechanism. The valve seat with the sealing hole provides a reliable sealing interface that is not affected by temperature or pressure conditions. The pressing part only needs to control the valve hole's opening and closing, not maintain continuous extrusion force. This allows the sample solution to be successfully extracted even when ambient temperature is low or negative pressure is large.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of operation

If the sample inlet channel is opened by self-reset, then the sample solution can flow, but the channel cannot be reliably closed or opened

Engineering Contradiction:
Improvesample solution flow controlVSAvoidchannel opening and closing reliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The valve core with its valve hole and valve seat structure provides a reliable mechanical control mechanism. The pressing part can reliably close the valve hole by pressing the valve core against the valve seat, and the valve hole can be reliably opened by releasing the pressing force. This intermediary structure ensures consistent and reliable opening and closing operation, eliminating the uncertainties of self-reset mechanisms.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution enhances the reliability of sample solution control, preventing leakage and ensuring successful extraction, thereby improving the accuracy and consistency of detection processes in in-vitro diagnostic analyzers.

Implementation Method 1

The air inlet channel includes an air outlet hole and an air inlet hole. The air inlet hole is provided on a surface of the installation body. The air outlet hole is configured for communication with the sample tube provided on the installation hole.

Methodology Applied
Scientific EffectGas flow through channel:

Implementation Method 2

The sealing portion is in sealing fit with an outer wall of the sample tube.

Methodology Applied
Scientific EffectSealing fit:

Data Source

PatentUS20230078497A1In-vitro diagnostic analyzer, reagent card, and installation structure
Publication Date: 2023.03.16 GUANGZHOU WONDFO BIOTECH
  • US20230078497A1 patent drawing
  • US20230078497A1 patent drawing
  • US20230078497A1 patent drawing

AI summary

An in-vitro diagnostic analyzer, a reagent card (10), and an installation structure (200) are disclosed. The installation structure (200) includes an installation body (210). The installation body (210) includes an installation hole (212) configured to sleeve a sample tube (70), a hollow needle (220), a sealing portion (240), and an air inlet channel (230). One end of the hollow needle (220) is capable of being inserted into the sample tube (70). The sealing portion (240) is in sealing fit with an outer wall of the sample tube (70). The air inlet channel (230) includes an air outlet hole (234) and an air inlet hole (232). The air outlet hole (234) is configured for communication with the sample tube (70) provided on the installation hole (212). The reagent card (10) is integrated with the installation structure (200), and the in-vitro diagnostic analyzer is integrated with the reagent card (10).