Diagnostic Chewing Gum for Pathogen Detection

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Solution Overview

Problem

Current methods for identifying pathogens in the mouth cavity and adjacent tissues are complex and require advanced instrumentation, making them unsuitable for immediate or self-monitoring applications.

Innovation Solution

A diagnostic chewing gum with embedded or attached particles that change detectably upon contact with pathogen-specific markers, allowing for the identification of pathogens such as viruses, bacteria, or fungi through the human senses, specifically the taste system, without the need for additional analytical tools.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If advanced instrumentation and specialized center systems are used for pathogen identification, then measurement precision and reliability are improved, but device complexity and ease of operation deteriorate

Engineering Contradiction:
Improvepathogen identification accuracyVSAvoidinstrumentation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the pathogen detection function from complex centralized laboratory systems and embeds it into a simple chewing gum device. The gum contains specific elements that interact with pathogen markers directly in the oral cavity, eliminating the need for complex instrumentation while maintaining detection capability through direct sensory feedback to the user.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The chewing gum enables self-monitoring of pathogen presence without requiring specialized personnel or equipment. The user simply chews the gum and perceives changes through sensory systems (taste, smell, texture), allowing autonomous pathogen detection and eliminating dependency on complex external analytical systems.

Inventive Principle:
Principle #25Self-service

2Measurement precision

If advanced instrumentation is used for pathogen analysis, then measurement precision is improved, but ease of operation and accessibility deteriorate

Engineering Contradiction:
Improvepathogen detection accuracyVSAvoidself-monitoring capability
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent replaces complex mechanical and electronic analytical instruments with human sensory systems. The chewing gum translates pathogen presence into sensory perceptions (taste changes, odor, texture modifications), allowing the user's biological sensing apparatus to perform the measurement function that would otherwise require sophisticated equipment.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The chewing gum serves multiple functions: it acts as a diagnostic tool for pathogen detection, a therapeutic agent for oral health, and a convenient delivery system. This multi-functionality integrates complex detection capabilities into a universally usable format that requires no special training or equipment.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If complex analytical systems are deployed, then reliability of pathogen identification is improved, but loss of time and productivity deteriorate

Engineering Contradiction:
Improvepathogen identification reliabilityVSAvoiddetection time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The chewing gum performs pathogen detection in advance, enabling early identification before symptoms develop or before clinical consultation. By continuously monitoring during chewing, the system provides immediate feedback that allows preemptive action, eliminating the time delay associated with sending samples to specialized laboratories for analysis.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables patient self-monitoring for pathogen presence, facilitating early detection and potential intervention, shifting point-of-care diagnosis to self-monitoring and enabling pre-emptive, non-invasive treatment strategies.

Implementation Method 1

Said element generates the change upon direct or indirect contact with a marker which is released by said pathogens

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Data Source

PatentUS9526803B2Diagnostic chewing gum for pathogens
Publication Date: 2016.12.27 JULIUS MAXIMILIANS UNIV WURZBURG
  • US9526803B2 patent drawing
  • US9526803B2 patent drawing
  • US9526803B2 patent drawing

AI summary

Described herein is a diagnostic chewing gum for identifying the presence of pathogens detectable via the mouth, in particular pathogens residing in nasal, oropharyngeal, laryngeal, oesophageal, ocular and/or pulmonal tissue of a user, more particularly pathogens selected from among a virus, bacterium, protozoa, prion, fungus or a combination thereof. The inventive diagnostic chewing gum includes a base material or particles (3) embedded and/or attached to the base material and an element (1, 5-7), like e.g. a releasable flavor molecule, attached to the base material and/or the particles, for the generation of a change in the chewing gum directly detectable by the user, wherein the element (1, 5-7) generates the change upon direct or indirect contact with a marker (4) which is released by the pathogens, or, in case of a virus or prion, by the cellular structure hosting it.