Diagnostic Kit Sample Flow Control for Detection Accuracy
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Solution Overview
Problem
Current diagnostic kits face challenges in accurately diagnosing diseases due to the fast movement of diagnostic samples through flow channels, leading to insufficient pretreatment and inaccurate optical information detection, which reduces detection accuracy.
Innovation Solution
A diagnostic kit that incorporates a diagnostic sample movement regulation unit to control the movement of the diagnostic sample through a flow channel, allowing for precise movement and stationary detection, combined with a controller that operates the diagnostic chip and optical information detection unit to optimize sample interaction with pretreatment and test materials.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If the diagnostic sample moves quickly through the flow channel, then the diagnostic process is faster, but there is not enough time for pretreatment and optical information detection, reducing diagnostic accuracy
Solution Approach 1:
The system dynamically adjusts the movement speed of the diagnostic sample through the flow channel. The controller regulates the driving mechanism to control the sample's movement, allowing it to move quickly when needed but slow down or pause at specific positions for pretreatment and optical information detection. This dynamic speed control resolves the contradiction between fast diagnostic processing and accurate measurement.
2Productivity
If optical information is detected during sample traveling, then the process is continuous, but only one measurement per area is possible, reducing detection accuracy
Solution Approach 1:
The system implements periodic action by controlling the sample to move to specific detection positions and pause there for a predetermined period. The controller regulates the driving mechanism to bring the sample to the detection area, hold it stationary for multiple measurements, then move it forward. This periodic stop-and-detect cycle enables multiple measurements at each location while maintaining overall process continuity, resolving the contradiction between detection efficiency and accuracy.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables more accurate disease diagnosis by allowing sufficient reaction time for samples with materials, enabling multiple measurements at the same location, thereby improving detection accuracy and simplifying the diagnostic process.
Implementation Method 1
an optical information detection unit detecting optical information on the diagnostic sample
Data Source
AI summary
A diagnostic kit includes: a diagnostic chip formed with a flow channel through which a diagnostic sample moves; a diagnostic sample movement regulation unit opening/closing one end of the flow channel to regulate movement of the diagnostic sample; an optical information detection unit detecting optical information on the diagnostic sample; and a controller controlling operation of the diagnostic sample movement regulation unit and the optical information detection unit, wherein the optical information detection unit includes: a light source illuminating the diagnostic sample; and a sensor sensing the optical information from the diagnostic sample, the diagnostic sample movement regulation unit is operatively associated with the optical information detection unit, and the diagnostic chip and the optical information detection unit are moved relative to each other upon operation of the diagnostic sample movement regulation unit.