Dialysate Regenerator Flow Portioning for Stable Dialysis Recycling

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Solution Overview

Problem

Existing dialysis apparatuses utilize fresh dialysate in pouches and dispose of used dialysate, generating waste, necessitating an improved dialysis system that recycles spent dialysate.

Innovation Solution

A dialysate regenerator that includes a regenerator inlet, outlet, hydraulic circuit, and fluid portioning system to convert spent dialysate into regenerated dialysate using purification means, such as an adsorber, with a movable separator wall and flow adjuster to maintain consistent pressure and flow, and a housing with replaceable components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of substance

If fresh dialysate is used and disposed after single use, then dialysis treatment can be performed, but waste is generated and resource efficiency deteriorates

Engineering Contradiction:
Improvedialysate wasteVSAvoiddialysis treatment continuity
Core Design Contradiction:
Loss of substanceVSProductivity

Solution Approach 1:

The patent recovers spent dialysate by capturing it in a collection container and regenerating it through a multi-step process involving carbonation, deionization, and filtration. The regenerated dialysate is then returned to the dialysis apparatus for reuse, eliminating waste and enabling continuous operation without requiring constant supply of fresh dialysate pouches.

Inventive Principle:
Principle #34Discarding and recovering

Solution Approach 2:

The system enables continuous dialysis treatment by automatically regenerating dialysate in real-time. The regeneration loop operates continuously, with spent dialysate being processed and regenerated dialysate being fed back into the dialysis apparatus, ensuring uninterrupted treatment capability and eliminating the need for frequent pouch changes.

Inventive Principle:
Principle #20Continuity of useful action

2Ease of manufacture

If spent dialysate is disposed immediately, then disposal simplicity is maintained, but resource efficiency and environmental impact worsen

Engineering Contradiction:
Improvedisposal simplicityVSAvoiddialysate recovery
Core Design Contradiction:
Ease of manufactureVSLoss of substance

Solution Approach 1:

The system performs automatic self-regeneration of dialysate without requiring manual intervention. The regeneration process is automated through controlled carbonation, deionization, and filtration steps, with the system automatically capturing spent dialysate, processing it, and returning it to the dialysis apparatus, eliminating the need for manual disposal operations.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent introduces an intermediary regeneration system between the dialysis apparatus and the environment. This intermediary system captures spent dialysate, processes it through carbonation and deionization, and returns purified dialysate to the apparatus, preventing direct disposal and enabling resource recovery.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of substance

If dialysate is regenerated through purification, then resource efficiency improves, but system complexity increases

Engineering Contradiction:
Improvedialysate recyclingVSAvoidregeneration system structure
Core Design Contradiction:
Loss of substanceVSDevice complexity

Solution Approach 1:

The regeneration system is segmented into distinct functional modules: a collection container for spent dialysate, a carbonation unit for CO2 addition, a deionization unit for salt removal, and a filtration unit for particulate removal. Each module performs a specific function, making the complex regeneration process manageable and easier to implement while maintaining high resource efficiency.

Inventive Principle:
Principle #1Segmentation

4Reliability

If pressure and flow are not controlled, then device simplicity is maintained, but treatment consistency and safety worsen

Engineering Contradiction:
Improvepressure stabilityVSAvoidflow control mechanism
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system incorporates pressure sensors and flow meters that continuously monitor the dialysate flow and pressure conditions. This feedback information is used to automatically adjust pump speeds, valve positions, and other control parameters to maintain stable pressure and consistent flow rates throughout the dialysis treatment, ensuring treatment reliability and patient safety.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The dialysate regenerator effectively recycles spent dialysate, reducing waste by converting it into regenerated dialysate with consistent pressure and flow, suitable for use in dialysis systems.

Implementation Method 1

the purification means may include a compartment including a toxin remover, for example, an adsorber

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

a chamber including a movable separator wall separating the interior of the chamber into a first compartment and a second compartment

Methodology Applied
Scientific EffectMechanical separation:

Implementation Method 3

a flow adjuster configured to detect an external flow or external pressure from one or each of the regenerator inlet and the regenerator outlet (individually) and adjust an internal flow or internal pressure so that the external flow or external pressure remains unchanged

Methodology Applied
Scientific EffectPressure regulation:

Data Source

PatentUS12485212B2Dialysate regenerator and system comprising the same
Publication Date: 2025.12.02 TEMASEK POLYTECHNIC
  • US12485212B2 patent drawing
  • US12485212B2 patent drawing
  • US12485212B2 patent drawing

AI summary

An aspect of the disclosure relates to a dialysate regenerator for connecting to a dialysis apparatus, the dialysate regenerator including a regenerator inlet for receiving dialysate; a regenerator outlet for dispensing regenerated dialysate; a hydraulic circuit connected between the regenerator inlet and the regenerator outlet, and further including a fluid portioning system to divide a dialysate flow into uniform portions for sequential regeneration An aspect of the disclosure relates to a dialysis system including a dialysis apparatus including: a fresh dialysate input; a spent dialysate output; and the dialysate regenerator, wherein the regenerator inlet may be coupled to the spent dialysate output for receiving spent dialysate, and wherein the regenerator outlet may be coupled to the fresh dialysate input for dispensing regenerated dialysate.