Dialyser Flow Direction Detection via Clearance Measurement

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Solution Overview

Problem

Current blood treatment devices, such as dialyzers, often operate in countercurrent flow to ensure effective dialysis, but incorrect connections can lead to co-current flow, reducing treatment efficacy and safety, as existing methods lack reliable indicators to distinguish between correct and incorrect flow directions.

Innovation Solution

A device and method that measure clearance values and compare them to specified limits, and adjust dialysate flow rates to determine the flow direction, utilizing a measuring unit and arithmetic/evaluation unit to differentiate between countercurrent and co-current flow operations, ensuring safe and effective dialysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual connection of dialyser to fluid system is used, then ease of operation is improved, but reliability deteriorates due to risk of incorrect connection

Engineering Contradiction:
Improveease of connectionVSAvoidflow direction correctness
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent implements a feedback mechanism by measuring clearance values during dialysis operation and comparing them against expected ranges for countercurrent flow. The system provides real-time feedback to the operator about whether the dialyser is correctly connected, allowing correction of incorrect connections while maintaining manual operation simplicity.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces mechanical connection verification methods with electronic sensing and computational analysis. Instead of relying on physical indicators or manual verification, the system uses clearance measurement devices, sensors, and arithmetic evaluation to detect flow direction and provide automated verification of correct connection.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If clearance measurement and evaluation system is added, then reliability is improved by detecting flow direction, but device complexity increases

Engineering Contradiction:
Improveflow direction detectionVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent integrates the clearance measurement and evaluation functions into the existing dialysis machine architecture. The same hardware components (pumps, sensors, control units) that perform dialysis functions are also utilized for clearance measurement and flow direction detection, eliminating the need for separate dedicated verification devices and reducing overall system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system performs self-verification by automatically measuring clearance values, comparing them against pre-stored reference ranges, and generating alerts for incorrect connections without requiring external verification equipment or complex additional subsystems. The dialysis machine essentially verifies its own correct operation.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach increases the safety of blood treatment by reliably detecting and correcting flow direction, preventing inefficient dialysis and potential harm to patients by ensuring operation in the standard countercurrent flow.

Implementation Method 1

the blood and the dialysate flowing along the membrane of the dialyser or filter in opposite directions... a dialyser or filter, which is divided into a blood chamber and a dialysate chamber by a semi-permeable membrane

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 2

a dialyser or filter, which is divided into a blood chamber and a dialysate chamber by a semi-permeable membrane

Methodology Applied
Scientific EffectOsmosis: Osmosis

Data Source

PatentUS10639411B2Device for identifying the direction of liquid flow through a dialyser
Publication Date: 2020.05.05 FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
  • US10639411B2 patent drawing
  • US10639411B2 patent drawing

AI summary

The invention relates to a device and a method for detecting the direction of fluid flow through a dialyser 1 which comprises a blood chamber 4, through which blood flows, and a dialysate chamber 3, through which dialysate flows, which are separated from one another by a semi-permeable membrane 2. In addition, the invention relates to an extracorporeal blood treatment device comprising a device for detecting the flow direction. A first aspect of the invention is to measure the clearance in order to detect the flow direction and to compare the measured clearance with a specified limit value, a flow direction in countercurrent flow being concluded if the clearance is greater than the specified limit value. This aspect is based on the finding that in the case of blood treatment in practice with operation of the dialyser in co-current flow, clearance values above a certain limit value can no longer be achieved. A second aspect of the invention is to measure the clearance to detect the flow direction and to change the flow rate of the dialysate. Checking the flow direction according to the second aspect is based on the comparison of the measured change in clearance with a calculated expected value of the change in clearance for operation of the dialyser in both countercurrent flow and co-current flow. The invention according to the second aspect is based on the finding that the amount of the relative change in clearance in the event of a change in dialysate rate is always greater in the case of operation in co-current flow than in countercurrent flow.