Dialysis Cassette Conductivity Sensor Integration

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Solution Overview

Problem

Existing dialysis machines face challenges in monitoring sodium concentration in blood during dialysis due to the complexity of blood composition, leading to practicality, safety, and cost issues with disposable devices for measuring conductivity in plasmatic water.

Innovation Solution

A circuit for extracorporeal dialysis with a cassette containing conductive elements that allow conductivity measurements without external contact with plasmatic water, using hollow plugs with internal and external surfaces for electrode engagement, integrated within the dialysis machine for safe and practical conductivity and temperature measurement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a disposable device for measuring conductivity is used in contact with plasmatic water, then sodium concentration can be monitored, but practicality, safety, and cost problems arise

Engineering Contradiction:
Improvesodium concentration monitoringVSAvoidsafety and practicality
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent merges the conductivity measurement function directly into the dialysis cassette by integrating conductive elements (electrodes) into the plasmatic water conduction line. This eliminates the need for separate disposable measurement devices, allowing continuous monitoring while maintaining safety and reducing cost. The conductive elements are permanently installed in the cassette, which is already in contact with plasmatic water during dialysis.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent uses the dialysis cassette itself as an intermediary carrier for the conductive elements. Instead of placing measurement devices directly in contact with plasmatic water through external connections, the cassette structure serves as the medium that holds the electrodes in proper position and provides the necessary electrical connection path to the measurement device.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If external electrodes are used to measure conductivity in plasmatic water, then measurement is possible, but safety risks increase due to direct contact

Engineering Contradiction:
Improveconductivity measurementVSAvoidsafety risks
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The measurement function is merged into the dialysis cassette structure itself. The conductive elements are integrated into the plasmatic water conduction line, eliminating the need for external electrodes that would require direct contact with plasmatic water. This integration maintains measurement capability while removing safety hazards associated with external contact.

Inventive Principle:
Principle #5Merging (Combining)

3Measurement precision

If disposable devices are used for conductivity measurement, then measurement capability is provided, but cost increases

Engineering Contradiction:
Improveconductivity measurement capabilityVSAvoidcost
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent combines the conductivity measurement functionality with the existing dialysis cassette, eliminating the need for separate disposable measurement devices. The conductive elements are permanently installed in the cassette, allowing repeated use across multiple dialysis treatments. This integration reduces the quantity of disposable materials required and lowers overall treatment cost.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables safe, practical, and cost-effective monitoring of sodium concentration in blood by eliminating the need for external contact with plasmatic water, enhancing safety and operational efficiency.

Implementation Method 1

The cassette 7 comprises a plurality of conductive elements 9 as illustrated schematically in Figure 1... Each of the conductive elements 9 is constituted by a hollow plug 11 made of conductive material and presenting a surface 11a facing the inside of the compartment 8 and hence in contact with the plasmatic water

Methodology Applied
Scientific EffectElectrical Conductivity: Conduction (electrical)

Implementation Method 2

The dialysis machine 7 comprises a device 12 for measuring conductivity fixed to a panel 13 for covering the machine 7 itself... the device 12 for measuring conductivity comprises a plurality of electrodes 14, each of which engages a respective hollow plug 11

Methodology Applied
Scientific EffectConductivity measurement: Conduction (electrical)

Data Source

PatentEP2143378B1Dialysis cassette with conductivity sensor
Publication Date: 2011.09.07 BELLCO S R L CON UNICO SOCIO
  • EP2143378B1 patent drawingFigure 1~2

AI summary

A circuit for extracorporeal dialysis (1) comprising means for separation of plasmatic water (3) from the patient's blood, a line (6) for transport of the plasmatic water produced, and a cassette (5), provided inside which is at least one compartment (8) isolated in a fluid-tight way and forming part of the line (6) for transport of the plasmatic water; the cassette (5) comprises at least two conductive elements (9), each of which has a first surface of contact (11a) facing the inside of the compartment (8) and designed to be in contact with the plasmatic water, and a second surface of contact (11b) facing the outside of the cassette (5).