In-Line Dialysis Fluid Mixing With Load-Cell Composition Control

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Solution Overview

Problem

Existing dialysis systems face challenges in ensuring the purity and composition of dialysis fluids, particularly when using tap water as a water source, as they struggle to effectively remove contaminants and maintain the required quality for patient treatments.

Innovation Solution

A system is developed that includes a water purification system with multiple filtration stages and sensors to monitor and control the purification process, coupled with a proportioning system that uses load cell sensors to weigh dialysis fluid concentrates and a controller to ensure the mixture meets defined parameters, allowing for real-time adjustments and diversion of non-compliant fluids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple filtration stages are used to purify water, then the purity of dialysis fluid is improved, but the device complexity increases

Engineering Contradiction:
Improvepurity of dialysis fluidVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The water purification system is divided into multiple independent filtration stages, each targeting specific contaminants. This segmentation allows the system to achieve high purity levels while maintaining modularity, making the complex system easier to manage and maintain through discrete, functional units.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system performs preliminary filtration and purification actions before the main dialysis fluid preparation process. By pre-treating the water through multiple filtration stages and removing contaminants in advance, the system ensures that only purified water enters the mixing stage, thereby guaranteeing fluid purity without adding complexity to the core dialysis function.

Inventive Principle:
Principle #10Preliminary action

2Manufacturing precision

If load cell sensors and proportioning systems are used to control concentrate mixing, then the manufacturing precision of dialysis fluid composition is improved, but the device complexity increases

Engineering Contradiction:
Improvecomposition of dialysis fluidVSAvoiddevice complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

Load cell sensors continuously monitor the weight of concentrate being dispensed and provide real-time feedback to the proportioning system. This closed-loop feedback mechanism ensures precise control over the mixing ratios of dialysis concentrates, achieving accurate fluid composition while automating the process to reduce operational complexity.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system replaces manual measurement and mixing methods with automated electronic proportioning controlled by processors and sensors. This substitution of mechanical operations with electronic control systems achieves high manufacturing precision for fluid composition while reducing the need for manual intervention and simplifying operation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If sensors and real-time monitoring are implemented, then the reliability of dialysis fluid quality is improved, but the use of energy increases

Engineering Contradiction:
Improvequality of dialysis fluidVSAvoiduse of energy
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The monitoring system is designed to activate sensors and quality checks only when needed during the fluid preparation process, rather than continuous full-power operation. This partial action approach maintains reliable quality assurance while reducing overall energy consumption by optimizing when monitoring resources are deployed.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system ensures the production of dialysis fluids with consistent quality by preventing the use of impure mixtures, prolonging the life of purification components, and maintaining the necessary purity levels for effective dialysis treatments.

Implementation Method 1

an amount of the first dialysis fluid concentrate received by the mixing container is determined by a change in weight of at least one of: a first dialysis fluid concentrate source, the mixing container, or any combination thereof

Methodology Applied
Scientific EffectWeight measurement:

Implementation Method 2

a pump fluidly connected to the fluid conduit and configured to pump the first dialysis fluid concentrate and the second dialysis fluid concentrate

Methodology Applied
Scientific EffectPumping: Pump

Data Source

PatentUS20260034287A1In-line dialysis fluid preparation
Publication Date: 2026.02.05 MOZARC MEDICAL US LLC
  • US20260034287A1 patent drawing
  • US20260034287A1 patent drawing
  • US20260034287A1 patent drawing

AI summary

A system includes a fluid conduit to receive water from a water source, a first and second dialysis fluid concentrate. The system includes a pump fluidly connected to the fluid conduit and to pump the first and second dialysis fluid concentrate. The system includes a first and second dialysis fluid concentrate source fluidly connected to the pump and configured to store the first and second dialysis fluid concentrate, respectively. The system includes a processor configured to control an amount of mixing of the first dialysis fluid concentrate, the second dialysis fluid concentrate, and the water to output a dialysis fluid having a defined composition. The processor determines the defined composition of the dialysis fluid based on a change in weight of the first dialysis fluid concentrate source, the second dialysis fluid concentrate source, a mixing container configured to accommodate the dialysis fluid, or any combination thereof.