Patient-Specific Dialysis Mixing Apparatus with Concentration Control

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Solution Overview

Problem

Current dialysis and infusion solutions lack the ability to provide individualized compositions, leading to potential concentration imbalances that can be dangerous for patients, and existing apparatuses for mixing solutions are critical in terms of patient safety, risking excessive or insufficient dosages of substances.

Innovation Solution

A technical apparatus with multiple fluid inlets and a control device that allows for independent variation of substance concentrations within safe limits, ensuring that the final solution composition meets specific patient needs without exceeding approved concentration ranges, even in case of malfunctions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple concentrated solutions are stored and connected to blood treatment units, then individualized treatment formulations can be provided, but logistical outlay increases significantly due to frequent connection changes

Engineering Contradiction:

Improveindividualized treatment formulationVSAvoidlogistical outlay

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent combines multiple concentrated solution formulations into a single mixing apparatus. The system accepts multiple concentrated solution inputs (different formulations stored in one or more containers) and mixes them in controlled proportions to generate the required individualized treatment solution, eliminating the need to physically connect different formulation containers to the blood treatment unit.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The patent segments the solution delivery system into concentrated solution storage (separated by formulation type) and a centralized mixing station. The mixing apparatus divides the task of solution preparation into separate functional components: storage of concentrated formulations, controlled mixing, and delivery to the blood treatment unit, simplifying the overall logistical workflow.

Inventive Principle:

Principle #1Segmentation

2Adaptability or versatility

If concentrated solutions are mixed with water in defined ratios, then usable solutions with adjusted concentrations can be produced, but the ability to independently vary all substance concentrations is limited

Engineering Contradiction:

Improveconcentration adjustmentVSAvoidindependent substance variation

Core Design Contradiction:

Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The patent changes the concentration parameters of multiple concentrated solutions (each with different substance compositions) and combines them in controlled ratios. By varying the mixing proportions of different concentrated formulations, the system can independently adjust the concentration of multiple substances in the final usable solution, overcoming the limitation of fixed concentration ratios in single-constituent dilution.

Inventive Principle:

Principle #35Parameter changes

3Adaptability or versatility

If mixing apparatus allows free adjustment of substance concentrations, then patient-specific solutions can be produced, but the risk of exceeding safe concentration limits increases

Engineering Contradiction:

Improvepatient-specific compositionVSAvoidsafety within concentration limits

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The mixing apparatus incorporates control means that monitor and regulate the mixing process to ensure the final solution concentrations remain within safe therapeutic limits. The system uses feedback control to adjust mixing ratios and prevent excessive or insufficient dosages, maintaining reliability while enabling patient-specific solution customization.

Inventive Principle:

Principle #23Feedback

Solution Approach 2:

The patent performs preliminary mixing and concentration adjustment in a controlled environment before the solution reaches the patient. The mixing apparatus pre-calculates and pre-mixes the solution with verified concentrations, ensuring safety constraints are met before delivery to the blood treatment unit, rather than relying on post-mixing verification.

Inventive Principle:

Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the production of patient-specific dialysis or infusion solutions with freely adjustable substance compositions, ensuring safety by maintaining concentrations within therapeutic limits, thus preventing adverse effects on patients.

Implementation Method 1

substances and water are transported through the semipermeable membrane by the physical effects of diffusion and osmosis

Methodology Applied

Scientific EffectDiffusion: Diffusion

Implementation Method 2

substances and water are transported through the semipermeable membrane by the physical effects of diffusion and osmosis

Methodology Applied

Scientific EffectOsmosis: Osmosis

Implementation Method 3

the substance transport through the semipermeable membrane is caused by a pressure gradient, that is to say convectively

Methodology Applied

Scientific EffectConvection: Convection

Data Source

PatentUS20240148946A1Mixing apparatus for producing solutions, in particular of dialysis or infusion treatments

Publication Date: 2024.05.09 LOHSE MARVIN

AI summary

Mixing apparatus for producing solutions for medical treatment, in particular for administering dialysis or infusion solutions.