Dialysis Sensor Conductivity Feedback Control

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current dialysis machines lack efficient sensors and control systems for real-time monitoring and adjustment of dialysate preparation, particularly in onsite preparation of dialysate with varying patient-specific requirements, which can lead to suboptimal treatment outcomes.

Innovation Solution

A dialysis machine equipped with a sensor downstream of the additive introduction point to measure conductivity or other characteristics of the dialysate, coupled with a computerized controller to process these measurements, allowing for intermittent or selective introduction of additives like bicarbonate, and enabling protective measures and precise adjustment of dialysate composition.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a sensor is installed downstream of the additive introduction point to monitor dialysate composition, then the precision of dialysate preparation is improved, but the complexity of the device increases

Engineering Contradiction:
Improvedialysate composition controlVSAvoidsensor and control system
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent implements a feedback control system where a sensor downstream of the additive introduction point continuously monitors dialysate composition (conductivity, pH, or concentration). The controller receives this feedback signal and automatically adjusts the additive introduction rate to maintain the desired composition, thereby improving precision while managing system complexity through automated closed-loop control

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces manual monitoring and adjustment of dialysate composition with electronic sensing and automated control systems. The sensor detects composition parameters electrically (conductivity, pH), and the controller electronically regulates the additive introduction, substituting mechanical/manual operations with electronic systems to achieve precise control

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If real-time monitoring of reverse osmosis water quality is implemented, then the reliability of dialysis treatment is improved, but the cost of the system increases

Engineering Contradiction:
Improvetreatment safetyVSAvoidmonitoring system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements preliminary monitoring of reverse osmosis water quality before the water is used for dialysate preparation. The sensor detects contaminants or abnormal conductivity in the RO water upstream, and the controller prevents unacceptable water from proceeding to the dialysate mixing stage, thereby ensuring treatment reliability through advance detection and protective action

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses feedback control where the sensor continuously monitors RO water quality and provides real-time information to the controller. When abnormal conditions are detected, the controller automatically adjusts the dialysate preparation process or alerts the operator, creating a closed-loop safety mechanism that improves reliability

Inventive Principle:
Principle #23Feedback

3Adaptability or versatility

If intermittent additive introduction is used to adjust dialysate composition, then the adaptability of the treatment is improved, but the control system complexity increases

Engineering Contradiction:
Improvepatient-specific treatment adjustmentVSAvoidcontrol system
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent implements a dynamic control system where the additive introduction is not continuous but intermittently adjusted based on real-time sensor feedback and patient-specific requirements. The controller dynamically modifies the additive introduction rate, timing, and duration to achieve target dialysate composition, enabling adaptable treatment while managing control complexity through automated algorithms

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system achieves adaptability by dynamically changing operational parameters (additive concentration, flow rate, introduction timing) based on sensor feedback and treatment requirements. The controller adjusts these parameters intermittently to achieve patient-specific dialysate composition targets, enabling versatile treatment customization

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This setup allows for real-time monitoring and controlled adjustment of dialysate composition, ensuring optimal treatment conditions and preventing the use of unacceptable reverse osmosis water, thereby enhancing the safety and effectiveness of hemodialysis treatments.

Implementation Method 1

The sensor can be designed to sense the conductivity or another characteristic of the solution encountered downstream of the additive introduction point

Methodology Applied
Scientific EffectConductivity measurement: Conduction (electrical)

Data Source

PatentEP3016695B1Sensor and method of sensing for dialysis machine
Publication Date: 2019.03.13 FRESENIUS MEDICAL CARE HOLDINGS INC
  • EP3016695B1 patent drawingFigure 1
  • EP3016695B1 patent drawingFigure 2
  • EP3016695B1 patent drawingFigure 3

AI summary

A dialysis machine (100) useful in hemodialysis can process or treat a reverse osmosis water flow (302) received through the machine (100) to prepare a dialysate. The machine (100) can include an additive source (140) to introduce an additive, such as bicarbonate, to the reverse osmosis water flow (302). The machine (100) can include a sensor (150) in fluid communication with the additive introduction point (144) that can measure the conductivity or similar characteristic of the solution. During a first time period when additive is actively introduced to the reverse osmosis water flow (302), the sensor (150) can measure a relatively high conductivity value (306). During a second time period when additive is not introduced to the reverse osmosis water flow (302), the sensor (150) can measure a relatively low conductivity value (310). The dialysis machine (100) can include a controller (190) that processes these measurements to assist control and operation of the machine (100).