Dialysis system

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Solution Overview

Problem

Current dialysis systems are unsuitable for home use due to their large size, high energy consumption, water requirements, and noise levels, limiting the flexibility and convenience for patients with end-stage renal disease.

Innovation Solution

A compact, portable dialysis system that uses lower flow rates of dialysate and blood, consumes less energy, and can produce real-time pasteurized water from a household water source, enabling hemodialysis, ultrafiltration, and hemodiafiltration with improved control over ultrafiltration levels.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If current dialysis systems are used, then effective dialysis treatment can be provided, but the systems are too large and bulky to fit within a typical home

Engineering Contradiction:
Improvesystem sizeVSAvoidhome use capability
Core Design Contradiction:
Volume of moving objectVSAdaptability or versatility

Solution Approach 1:

The dialysis system is divided into separate functional modules including a water treatment module, dialysate preparation module, blood processing module, and control module. Each module can be independently optimized for size and function, allowing the overall system to be compact enough for home use while maintaining complete dialysis functionality.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Components are arranged in a nested configuration where smaller functional units are integrated within larger housing structures. The dialysate preparation system is nested within the main system housing, and fluid pathways are routed through integrated channels that minimize external volume requirements.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Use of energy by moving object

If current dialysis systems are used, then dialysis treatment can be performed, but they consume large amounts of energy and require enormous amounts of water

Engineering Contradiction:
Improveenergy consumptionVSAvoiddialysis treatment effectiveness
Core Design Contradiction:
Use of energy by moving objectVSProductivity

Solution Approach 1:

The system operates at lower flow rates for both dialysate and blood compared to conventional systems. The water treatment module uses optimized heating and cooling parameters that reduce energy consumption while maintaining water quality standards. Flow rate parameters are carefully controlled to achieve effective dialysis with minimal resource consumption.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The water treatment module recovers and reuses heat from outgoing dialysate to preheat incoming water, reducing the energy required for heating. The system monitors and adjusts its own operation to maintain efficiency, with sensors detecting flow rates and temperatures to optimize energy usage in real-time.

Inventive Principle:
Principle #25Self-service

3Ease of operation

If home dialysis systems are made available, then patient scheduling flexibility can be improved, but complex flow-balancing technology increases manufacturing cost

Engineering Contradiction:
Improvescheduling flexibilityVSAvoidmanufacturing cost
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

Complex mechanical flow-balancing mechanisms are replaced with electronically controlled pumps and valves that can be precisely programmed through software. The control system uses microprocessors to manage fluid flow, eliminating the need for complex mechanical flow dividers and reducing manufacturing complexity while improving operational flexibility.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The control system serves multiple functions including flow regulation, temperature control, treatment timing, and safety monitoring. This multi-functional approach eliminates the need for separate specialized components for each function, reducing overall system complexity and manufacturing cost while maintaining full dialysis capability.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Object-generated harmful factors

If home dialysis systems use solenoid valves for flow control, then flow management can be achieved, but high noise levels are generated

Engineering Contradiction:
Improvenoise levelVSAvoidflow control capability
Core Design Contradiction:
Object-generated harmful factorsVSEase of operation

Solution Approach 1:

Solenoid valves that generate high noise levels are replaced with electronically controlled proportional valves or peristaltic pumps that provide flow control through electronic means. These alternatives operate quietly while maintaining precise flow management capability, making the system suitable for home environments where noise would be problematic.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a more convenient and energy-efficient dialysis solution for home use, reducing patient burden and increasing treatment flexibility while maintaining effective waste removal and fluid management.

Implementation Method 1

a heat exchange system in thermal communication with the fluid flow pathway adapted to heat and cool the single fluid stream

Methodology Applied
Scientific EffectHeat exchange: Heat Exchanger

Implementation Method 2

a dialyzer having a blood side thereof and a dialysate side thereof, said dialyzer membrane separating said blood side of said dialyzer from said dialysate side of said dialyzer

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentEP2576024B1Dialysis system
Publication Date: 2019.10.16 OUTSET MEDICAL
  • EP2576024B1 patent drawingFigure 1~2
  • EP2576024B1 patent drawingFigure 3~4B
  • EP2576024B1 patent drawingFigure 4C~6

AI summary

A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.