Dialysis System Ultrafiltration Control via Three-Pump Segmentation

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Solution Overview

Problem

Current dialysis systems are large, energy-inefficient, and unsuitable for home use due to their size and high water consumption, lacking precise control over ultrafiltration levels.

Innovation Solution

A dialysis system utilizing three pumps to control fluid flow rates through a dialyzer, allowing for precise hemodialysis, ultrafiltration, and hemodiafiltration, with the third pump supplementing the second pump to achieve desired flow rates and levels of ultrafiltration, enabling efficient and controlled fluid management.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If current dialysis systems are used, then dialysis treatment can be performed, but the systems are large and unsuitable for home use

Engineering Contradiction:
Improvesuitability for home useVSAvoidsystem size
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The dialysis system is divided into separate functional modules including individual pumps for dialysate inflow, outflow, and ultrafiltration control. Each pump operates independently to perform specific functions, allowing the system to be compact while maintaining full dialysis functionality for home use

Inventive Principle:
Principle #1Segmentation

2Productivity

If current dialysis systems are used, then dialysis treatment can be performed, but they consume large amounts of energy and water

Engineering Contradiction:
Improvedialysis treatment capabilityVSAvoidenergy consumption
Core Design Contradiction:
ProductivityVSLoss of energy

Solution Approach 1:

The system optimizes operating parameters including pump speeds, flow rates, and pressure differentials to minimize energy consumption while maintaining effective dialysis treatment. The third pump provides precise ultrafiltration control that reduces overall energy and water usage compared to traditional systems

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If two pumps are used for dialysate flow, then basic dialysis function is achieved, but precise ultrafiltration control is lacking

Engineering Contradiction:
Improveultrafiltration control precisionVSAvoidnumber of pumps
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The fluid control function is segmented into three independent pumps: first pump for dialysate inflow, second pump for dialysate outflow, and third pump specifically for ultrafiltration. This segmentation allows precise control of ultrafiltration as a separate function while maintaining overall system manageability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The third pump serves multiple purposes including providing ultrafiltration control, adjusting dialysate flow rates, and enabling both hemodialysis and ultrafiltration modes within the same system, making the additional component worthwhile despite increased complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Volume of moving object

If home dialysis systems are made compact, then portability is improved, but precise ultrafiltration control is compromised

Engineering Contradiction:
Improvesystem compactnessVSAvoidultrafiltration control accuracy
Core Design Contradiction:
Volume of moving objectVSMeasurement precision

Solution Approach 1:

By segmenting the ultrafiltration control into a dedicated third pump, the system achieves precise control in a compact configuration. The independent pump allows accurate flow rate adjustment without requiring a large, complex flow-balancing mechanism

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent replaces complex mechanical flow-balancing technology with an electronically controlled third pump that provides precise ultrafiltration control through electronic flow rate adjustment, reducing mechanical complexity while improving control precision in a compact system

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a compact, energy-efficient, and portable solution for dialysis with precise control over ultrafiltration levels, enhancing the ability to perform dialysis in a home setting while maintaining effective waste removal and fluid management.

Implementation Method 1

a first pump for pumping dialysate into a dialyzer

Methodology Applied
Scientific EffectPumping: Pump

Implementation Method 2

a second pump for pumping dialysate out of the dialyzer

Methodology Applied
Scientific EffectPumping: Pump

Implementation Method 3

a third pump that provides improved control of a level of ultrafiltration

Methodology Applied
Scientific EffectUltrafiltration: Pressure Gradient

Implementation Method 4

a third pump for pumping the dialysate through the fluid outlet pathway

Methodology Applied
Scientific EffectPumping: Pump

Implementation Method 5

Diffusion is the principal mechanism in which dialysis removes waste products such as urea, creatinine, phosphate and uric acid, among others, from the blood

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 6

Ultrafiltration is a process in dialysis where fluid is caused to move across the membrane from the blood into the dialysate for the purpose of removing excess fluid from the patient's blood stream. Ultrafiltration is a result of a pressure differential between the blood compartment of the dialyzer and the dialysate compartment of the dialyzer

Methodology Applied
Scientific EffectUltrafiltration: Pressure Gradient

Implementation Method 7

Along with water, some solutes are also drawn across via convection rather than diffusion

Methodology Applied
Scientific EffectConvection: Convection

Data Source

PatentUS9545469B2Dialysis system with ultrafiltration control
Publication Date: 2017.01.17 OUTSET MEDICAL
  • US9545469B2 patent drawing
  • US9545469B2 patent drawing
  • US9545469B2 patent drawing

AI summary

Systems and methods are disclosed for performing hemodialysis that include fluid handling systems that provide accurate control over the type and level of hemodialysis being performed. The system includes a first pump for pumping dialysate into a dialyzer and a second pump for pumping dialysate out of the dialyzer. The system also includes a third pump that provides improved control of a level of ultrafiltration, hemodiafiltration, or both.