Integrated Dialyzer Centrifugal Pump With Maglev Rotor

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing blood treatment systems for renal failure are cumbersome, require multiple components, and are prone to errors during setup, leading to increased costs and potential contamination risks.

Innovation Solution

A centrifugal blood pump integrated into a dialyzer with a magnetically driven, magnetically levitating rotor, combined with a treatment module that includes a dynamic magnetic field-generating pump drive unit, simplifies setup and reduces components, enhancing performance and reducing contamination risks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If separate pump and dialyzer components are used in traditional blood treatment systems, then each component can be optimized independently, but the system becomes cumbersome, requires multiple components, and increases setup complexity and contamination risks

Engineering Contradiction:
Improvesystem complexityVSAvoidcontamination risk
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent integrates the centrifugal pump impeller directly into the dialyzer housing, creating a single unified component rather than separate pump and dialyzer units. This merging eliminates the need for multiple connections and interfaces, thereby reducing setup complexity and minimizing potential contamination points while maintaining the functional independence of both pumping and dialysis operations

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If traditional mechanical pumps with seals and bearings are used, then reliable pumping action is achieved, but hemolysis risk and contamination potential increase due to mechanical contact points

Engineering Contradiction:
Improvepumping reliabilityVSAvoidhemolysis risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces traditional mechanical pump components with seals and bearings with a magnetically driven centrifugal impeller system. The impeller is rotated by magnetic fields generated by external magnets positioned against the housing, eliminating mechanical contact points that could cause hemolysis or contamination while maintaining reliable pumping action through centrifugal force

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If multiple separate components are used in blood treatment systems, then functional flexibility is maintained, but setup time increases and extracorporeal tubing volume increases

Engineering Contradiction:
Improvefunctional flexibilityVSAvoidsetup time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

By integrating the pump impeller and dialyzer into a single housing structure, the patent reduces the number of separate components that need to be assembled and connected during setup. This consolidation directly reduces setup time and minimizes the volume of extracorporeal tubing required, while the modular design maintains functional flexibility for different blood treatment applications

Inventive Principle:
Principle #5Merging (Combining)

4Productivity

If the pump impeller is positioned away from the center of the dialyzer, then pumping efficiency is improved, but blood flow distribution to the dialysis membrane becomes uneven

Engineering Contradiction:
Improvepumping efficiencyVSAvoidblood flow distribution
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent positions the centrifugal pump impeller at the center of the dialyzer housing and uses the radial symmetry of the circular impeller design to ensure uniform blood flow distribution. The centrifugal force generated by the rotating impeller naturally distributes blood evenly across the dialysis membrane surface, maintaining both pumping efficiency and flow distribution stability through geometric symmetry

Inventive Principle:
Principle #14Spheroidality (Curvature)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The integrated system reduces setup time, minimizes extracorporeal tubing, lowers hemolysis risk, and decreases contamination potential, while allowing for easier and more reliable blood treatment procedures.

Implementation Method 1

a magnetically driven, magnetically levitating rotor

Methodology Applied
Scientific EffectMagnetic levitation: Maglev

Implementation Method 2

a dynamic magnetic field-generating pump drive unit

Methodology Applied
Scientific EffectMagnetic field generation: Magnetic Field

Implementation Method 3

liquid to be pumped enters the pump impeller along a center of the pump impeller... the liquid exits the impeller transverse to the central axis of the housing

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Implementation Method 4

Diffuse mass transport is predominant in hemodialysis (HD)... blood passes from the patient through a dialyzer that includes a semi-permeable membrane to separate the blood from a large volume of externally-supplied dialysis solution

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 5

The transportation of the small molecular substances through the semi-permeable membrane is determined mainly by the differences in concentration between the dialysate and the blood

Methodology Applied
Scientific EffectOsmosis: Osmosis

Implementation Method 6

in hemofiltration (HF) convective mass transport through a membrane is used

Methodology Applied
Scientific EffectConvection: Convection

Data Source

PatentEP4058095B1Centrifugal blood pump comprising a portion of a blood dialyzer
Publication Date: 2025.12.24 FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
  • EP4058095B1 patent drawingFigure 1
  • EP4058095B1 patent drawingFigure 2
  • EP4058095B1 patent drawingFigure 3

AI summary

Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.