3,5-Dicaffeoylquinic Acid Extraction for Sustainable Aphid Control

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Current methods for controlling the green peach aphid (Myzus persicae) on peach trees are either ineffective or environmentally harmful, and there is a lack of efficient and sustainable processes for obtaining 3,5-dicaféoylquinic acid and its derivatives, which have shown potential as repellents and toxins against aphids.

Innovation Solution

A process for extracting 3,5-dicaféoylquinic acid and its derivatives from non-tuberized roots of Ipomoea batatas and other Convolvulaceae plants, involving steps like collection, extraction with organic solvents, purification, and optional isomerization, to achieve high yields and purity, which can be used in compositions to combat aphids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical insecticides are used to control green peach aphid, then aphid control effectiveness is improved, but environmental harm and toxicity increase

Engineering Contradiction:

Improveaphid control effectivenessVSAvoidenvironmental harm and toxicity

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters by using naturally occurring phenolic compounds (3,5-diCQ and derivatives) instead of synthetic insecticides. These compounds are extracted from plant sources and exhibit aphicidal activity while being environmentally benign, thus maintaining control effectiveness while eliminating toxicity and environmental harm.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent utilizes readily available plant materials (artichoke, coffee, sunflower) as sources of active compounds. These natural sources are inexpensive and renewable, replacing expensive and persistent synthetic chemical insecticides with sustainable, biodegradable alternatives that break down naturally in the environment.

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

2Quantity of substance

If 3,5-dicaféoylquinic acid is extracted from plant sources, then availability of the compound is improved, but extraction complexity and purification difficulty increase

Engineering Contradiction:

Improveavailability of 3,5-dicaféoylquinic acidVSAvoidextraction and purification process complexity

Core Design Contradiction:

Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent applies extraction techniques to isolate 3,5-dicaféoylquinic acid from plant matrices. By using solvents to extract the active compound from sources like artichoke, coffee, and sunflower, the patent achieves effective separation of the desired substance from complex plant materials, improving availability while managing extraction complexity through established methodologies.

Inventive Principle:

Principle #2Taking out (Extraction)

Solution Approach 2:

The patent identifies multiple plant sources (artichoke, coffee, sunflower) that all contain 3,5-dicaféoylquinic acid or its derivatives. This multi-sourcing strategy provides flexibility in extraction, allowing selection of the most convenient or efficient source for a given application, thereby simplifying the overall process while ensuring compound availability.

Inventive Principle:

Principle #6Universality (Multi-functionality)

3Quantity of substance

If multiple plant sources are used for 3,5-dicaféoylquinic acid production, then compound availability is improved, but process standardization and quality control become more difficult

Engineering Contradiction:

Improvecompound availabilityVSAvoidprocess standardization and quality control

Core Design Contradiction:

Quantity of substanceVSManufacturing precision

Solution Approach 1:

The patent acknowledges that different plant sources yield varying concentrations and profiles of 3,5-dicaféoylquinic acid and its derivatives. By establishing standardized extraction and purification protocols that can be applied across different sources, the patent maintains consistent product quality and potency while leveraging the advantages of multiple plant materials for compound availability.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process enables the production of 3,5-dicaféoylquinic acid with purity greater than 90% and its derivatives, which effectively repel and toxic to aphids, providing a sustainable and environmentally friendly solution for aphid control.

Implementation Method 1

extraction with one or more organic solvents of the phenolic compounds

Methodology Applied

Scientific EffectExtraction:

Implementation Method 2

extraction with one or more organic solvents of the phenolic compounds

Methodology Applied

Scientific EffectDissolution: Solvation

Implementation Method 3

spontaneous isomerization of said extracts under alkaline pH conditions

Methodology Applied

Scientific EffectIsomerization:

Data Source

PatentEP2237665B1Method for preparing dicaffeoylquinic acids and use thereof in combating aphids

Publication Date: 2013.10.30 INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

Figure 1
Figure 2~2A
Figure 2B~2E

AI summary

Method for preparing 3,5-dicaffeoylquinic acid and certain derivatives thereof, and use thereof in the preparation of plant-protection products. Method for combating aphids using 3,5-dicaffeoylquinic acid and certain derivatives thereof.